特应性皮炎患者血清变应原特异性IgE定量检测的临床意义  

Clinical Significance of Quantitative Measurement of Serumal Allergen-Specific-IgE of Atopic Dermatitis

作　　者：雍磊[1] 程相铎[1] 董自立[1] 李波[1] 何静[1] 王宇杰[1] 

机构地区：[1]解放军第150医院皮肤科,河南洛阳471031

出　　处：《临床军医杂志》2010年第1期71-73,共3页Clinical Journal of Medical Officers

摘　　要：目的探讨不同人群特应性皮炎(AD)患者血清变应原特异性IgE的临床意义。方法选择AD患者136例分为儿童组98例和成人组38例,并设正常对照组38例。采用德国PCA过敏原检测仪应用固相酶斑点技术,定量检测患者血清变应原特异性IgE。结果儿童组牛奶、蛋白、蛋黄、花生、曲霉菌属、分枝孢子菌属、鱼类等食物和霉菌变应原特异性IgE阳性率及检测结果较高,而成人组则为屋尘螨、粉尘螨、桦树花粉、艾属花粉、牧草花粉等花粉和螨;对照组大多为阴性或弱阳性。结论儿童组和成人组AD患者变应原特异性IgE种类有所不同(P<0.01),且其血清特异性IgE检测结果差异也有统计学意义(P<0.01)。Objective To investigate clinical significance of quantitative measurement of serumal allergen-specific-IgE of atopic dermatitis in different group. Methods 136 patients of atopic dermatitis were allocated by age, 98 in children group, 38 in adult group, adding 38 normal controls. Quantitative measuring of serumalallergen-specifie-IgE of atopie dermatitis was performed with solid phase enzyme spotting technique by PCA Allergy Test System made in German. Results Cow＇ s milk , egg white, Egg yolk, Peanut, Aspergillus, Cladosporium are major allergens of children group, but major allergens of children group are dermatophagoides pteronyssinus, dermatophagoides farinae, Birch pollen, mugwort pollen, timothy pollen. Allergens Of normal controls are negative or weakly positive. Conclusion The AD patients allergen-specific-IgE are different between children and adult group（ P 〈 0.01 ）. The values of serumal allergen-specific-lgE of atopic dermatitis of two groups are significant difference（ P 〈 0.01 ）.

关 键 词：特应性皮炎 变应原特异性IgE 阳性率 固相酶斑点技术 

分 类 号：R758.2[医药卫生—皮肤病学与性病学]