机构地区:[1]北京大学第一医院妇产科,100034 [2]首都医科大学附属北京妇产医院产科 [3]北京市海淀区妇幼保健院产科 [4]北京大学第三医院妇产科
出 处:《中华妇产科杂志》2010年第2期99-103,共5页Chinese Journal of Obstetrics and Gynecology
基 金:北京市科学技术委员会重大项目(20005190000091)
摘 要:目的探讨北京地区早产发生现状及不同孕周、不同类型早产儿的结局。方法选择2006年12月1日-2007年5月31日在北京大学第一医院(北大一院)、首都医科大学附属北京妇产医院(市妇产医院)、北京市海淀区妇幼保健院(海淀妇幼)、北京大学第三医院(北大三院)住院分娩的孕28周-36周“早产产妇955例及其早产儿1066例为研究对象,4家医院同期分娩数为15197例。结果(1)早产发生率:早产总发生率为6.3%(955/15197)。其中北大三院的早产发生率为13.1%(150/1142),北大一院的早产发生率为8.1%(125/1549),市妇产医院的早产发生率为5.5%(369/6656),海淀妇幼的早产发生率为5.3%(311/5850)。其中北大三院的早产发生率明显高于其他医院(P〈0.01)。两家综合医院(北大一院及北大三院)的早产率10.2%(275/2691)明显高于两家专科医院(市妇产医院及海淀妇幼)的早产率5.4%(680/12506),两者比较,差异有统计学意义(P〈0.01)。(2)早产发生孕周:〈34周的早产发生率为28.5%(272/954),t〉34周的早产发生率为71.5%(682/954),早产主要发生在孕34周以后。各家医院的早产发生孕周分布有明显不同,其中,海淀妇幼〈34周的早产发生率明显低于其他3家医院(P〈0.01),北大一院〈34周的早产发生率最高(P〈0.05),北大三院与市妇产医院相比较,差异无统计学意义(P〉0.05)。(3)早产发生的原因:在早产的发生原因排序中,未足月胎膜早破(PPROM)早产占首位(405例),其次为医源性早产(340例)和自发性早产(205例)。各医院早产发生的原因有所不同,北大三院的医源性早产率明显高于其他各医院(P〈0.01);北大一院的PPROM发生率较高而自发性早产率较低。医源性早产的发生原因排序中前4�Objective To investigate the incidence and relevant information of preterm birth and the outcomes of preterm infants delivered at various gestational weeks and for different causes. Methods Totally 955 women, who ended their pregnancies before term, and 1066 neonates of the previous mothers were enrolled in this survey, among 15 197 deliveries at Peking University First Hospital, Beijing Gynecological and Obstetric Hospital, Women's and Children's Hospital of Haidian District and Peking University Third Hospital, respectively, from December 1^st, 2006 to May 31^st, 2007. Results ( 1 ) Incidence of preterm birth: The overall incidence of preterm birth of the 4 hospitals was 6. 3% (955/15 197), and it was 8. 1% (125/1549) in Peking University First Hospital, 13.1% (150/1142), which was the highest (P 〈0. 01 ), in Peking University Third Hospital, 5.5% (369/6656) in Beijing Gynecological and Obstetric Hospital and 34. 0% (311/5850) in Women's and Children's Hospital of Haidian District. The preterm birth rate at the two comprehensive hospitals was significantly higher than that of the two specialized hospitals [ 10. 2% (275/2691) vs 5.4% (680/12 506), P 〈 0. 01 ]. (2) Gestational weeks at delivery : The incidence of preterm birth before 34 weeks was 28.5% (272/954) and the number changed to 71.5% (682/954)for those preterm deliveries after 34 weeks. However, this number varied among the 4 hospitals. Peking University First Hospital had the highest incidence of preterm birth before 34 weeks ( P 〈 0. 05), and the lowest was found in Women's and Children's Hospital of Haidian District(P 〈0. 01 ), but no difference was found between Peking University Third Hospital and Beijing Gynecological and Obstetric Hospital. (3) Etiology of preterm birth : Preterm premature rupture of membranes (PPROM) accounted for the most proportion of all preterm birth cases, followed by iatrogenic preterm birth and spontaneous preterm birth. But the caus
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