3467例输血前患者血清传染性疾病指标检测及分析  

Determination and analysis on serum infected makers of 3467 cases before transfusion

作　　者：张忠源[1,2] 池细弟[1,2] 胡望平[1,2] 叶桂云[1,2] 吴文辉[1,2] 

机构地区：[1]福建医科大学教学基地 [2]南平市第一医院,353000

出　　处：《检验医学与临床》2010年第4期306-307,共2页Laboratory Medicine and Clinic

摘　　要：目的对本院输血前患者进行乙肝病毒(HBV)、丙肝病毒(HCV)、艾滋病毒(HIV)以及梅毒(TP)等传染病的检测,了解南平地区输血前患者传染病情况,以防范患者、医务人员院内感染及医疗纠纷。方法采用酶联免疫法对3467例输血前患者进行乙肝表面抗原(HBsAg)、抗-HCV和抗-HIV检测,同时用梅毒甲苯胺红颗粒凝集试验(TRUST)初筛,梅毒螺旋体特异性抗体试验(TPPA)确证。结果HBsAg阳性率14.74%(511例),梅毒抗体经TRUST法检测阳性率2.11%(73例),再经TPPA确诊阳性率1.90%(66例)。抗-HCV阳性率0.40%(14例)、抗-HIV阳性率0.09%(3例)。结论本地区输血前患者血清4项传染性疾病指标有0.09%～14.74%的阳性率;HBV、HCV、TP感染率高于其他地区;HIV感染率低于其他地区。Objective To investigate the positive rates of HBV, HCV, HIV and syphilis infections of pre-oper ation and pre-blood transfusion patients and to know the status of infectious diseases before transfusion and operation for preventing and avoiding nosocomial infectious disease, medical worker＇s occupational exposure and preventing medical dissension. Methods 3 467 cases before transfusion and operation were enrolled. HBsAg anti-HCV and anti HIV were detected by ELISE method. At the same time,using TRUST titre and TPPA to confom syphilis positive. Results HBsAg（＋） 14.74%,syplilis（＋） 2.11% by TRUST method and sypilis（-） 1.90% by TPPA method, HCV（＋ ） 0.40%, HIV（ ＋ ） 0.09%. Conclusion Before this local blood transfusion, the patient blood serum four infectious targets have the positive rate of 0.09- 14.74%;the infection rate of hepatitis B virus, hepatitis C virus and syphilis is higher than that in other areas;the H IV infection rate is lower than that in other areas.

关 键 词：输血相关传染病 临床检测 输血安全 

分 类 号：R446.1[医药卫生—诊断学] R457.1[医药卫生—临床医学]