中心静脉导管相关性感染的病原学研究  

STUDY ON PATHOGENS OF CENTRAL VENOUS CATHETER-RELATED INFECTIONS

作　　者：李春梅[1] 钟晓祝[1] 杨艳[1] 谭细兰[1] 

机构地区：[1]南方医科大学珠江医院感染管理科,广州510282

出　　处：《现代预防医学》2010年第5期943-944,共2页Modern Preventive Medicine

基　　金：广东省医学科研基金(2006422)

摘　　要：[目的]了解中心静脉导管相关性感染(CVC-RI)的病原菌分布情况,加强监控。[方法]前瞻性调查215例留置中心静脉导管的患者,在治疗结束后或怀疑感染时拔管进行导管尖端细菌培养。[结果]导管尖端细菌培养215例,59例检有病原菌,检出率为27.44%。从59例阳性标本中共分离出61株病原菌,革兰阳性球菌23株(37.7%),革兰阴性杆菌23株(37.7%),真菌15株(24.6%)。位于前5位的细菌是表皮葡萄球菌(13.1%)、克柔假丝酵母菌(11.2%)、金黄色葡萄球菌(9.8%)、铜绿假单胞菌(6.6%)、不动杆菌(6.6%)。[结论]导管相关性感染病原菌以葡萄球菌为主,其次是克柔假丝酵母菌,均为表皮常见菌,因此,加强置管部位皮肤消毒、保持置管部位皮肤清洁、干燥是预防中心静脉导管相关性感染的重要措施。[Objective] To study the incidence of central venous catheter-related infections and distribution of pathogens,based on which strengthen inspection measures against these infection.[Methods] Studied 215 cases of indwelling central venous catheters prospectively,and then cultured bacteria on catheter tip after extubation at the end of treatment or suspected infection.[Results] The total strains of bacteria on catheter tip culture were 215,among which 59 cases were detected for pathogens,the detection rate was 27.44%.We isolated 61 strain from 59 positive specimens,among which gram-positive cocci were 23（37.7%）,gram-negative bacilli were23（37.7%）,fungi were 15（24.6%）.Located in the top five were Staphylococcus epidermidis（13.1%）,Candida krusei（11.2%）,Staphylococcus aureus（9.8%）,Pseudomonas aeruginosa（6.6%）,Acinetobacter（6.6%）.[Conclusion] The most pathogens of catheter-related infections are Staphylococcus,followed by Candida krusei.Maintaining catheter site clean and dry is the important measure to prevent central venous catheter-related infections.

关 键 词：中心静脉导管相关性感染 病原菌 

分 类 号：R37[医药卫生—病原生物学]