宁神合剂治疗妇女更年期失眠症临床观察  

Clinical observation of "Ningshen Mixture" in treating insomnia in climacteric women

作　　者：叶玉妹[1] 杨慰[1] 张晓丹[1] 吴文雯[1] 

机构地区：[1]上海市第七人民医院中医科,上海200137

出　　处：《上海中医药杂志》2010年第2期47-48,80,共3页Shanghai Journal of Traditional Chinese Medicine

基　　金：上海市浦东新区社会发展局卫生科技项目(PW2006A-25)

摘　　要：目的观察宁神合剂治疗妇女更年期失眠症的临床疗效及安全性。方法将64例更年期失眠症妇女随机分成治疗组33例和对照组31例。治疗组给予宁神合剂,对照组予地西泮片口服,治疗2个月。观察SPIEGEL量表、药物副反应量表(TESS)等评分,并评价临床疗效。结果两组治疗后疗效比较差异无统计学意义(P>0.05);与对照组同期比较,治疗组治疗2周后各项积分差异均有统计学意义,治疗4周后除睡眠时间、醒后感觉外各项积分差异均有统计学意义,至治疗8周后仅醒后感觉1项积分差异有统计学意义(P<0.05)。结论宁神合剂治疗妇女更年期失眠症疗效良好。Objective To observe the clinical effect and safety of ＂Ningshen Mixture＂ in treating insomnia in climacteric women. Methods Sixty-four cases were randomly divided into two groups： 33 cases in treatment group were treated with ＂Ningshen Mixture＂, while 31 cases in control group received diasepam, with a treatment course of two months. The scores of SPIGEGL scale and TESS scale were observed, and the clinical efficacy was evaluated. Results There was no significant difference between the two groups in clinical efficacy（ P 〉0.05 ）. Compared with the same time in the control group, there were significant differences in the scores of every item after 2-week treatment, in all the scores except for sleeping time and awakening sensation after 4-week treatment, and awakening sensation after 8.week treatment in SPIGEGL scale in the treatment group（ P 〈0.05 ）. Conclusion ＂Ningshen Mixture＂ is effective for climacteric women with insomnia.

关 键 词：妇女更年期 失眠 宁神合剂 SPIEGEL量表 副反应量表 

分 类 号：R271.116[医药卫生—中医妇科学] R256.23[医药卫生—中医学]