发热门诊3063例患者甲型H1N1流感筛查  

Screening for influenza A （H1N1 ） from 3 063 patients in fever clinic

作　　者：罗洁[1] 卢业成[2] 张复春[3] 洪文昕[3] 余卫华[1] 胡凤玉[2] 陈铿[1] 尹炽标[3] 唐小平[3] 杨湛[3] 

机构地区：[1]广州市第八人民医院发热门诊,510060 [2]广州市第八人民医院检验科,510060 [3]广州市第八人民医院感染病科,510060

出　　处：《中华临床感染病杂志》2010年第1期5-8,共4页Chinese Journal of Clinical Infectious Diseases

基　　金：国家科技支撑计划（甲型H1N1流感联防联控应急科研项目）

摘　　要：目的总结甲型H1N1流感的流行特征和临床表现，探索早期筛查的有效方法。方法对2009年5月2日-10月31日在广州市第八人民医院发热门诊就诊的患者进行甲型H1N1流感筛查，并对其流行病学资料、临床症状和实验室检测结果进行分析。结果在3063例接受筛查的病例中，共有272例（8．88％）被确诊为甲型H1N1流感，其中重症病例23例（8．46％）。190例患者以发热为首发症状，其他常见的症状有咳嗽、咽痛和头痛等。重症病例可出现肌酸激酶同工酶（CK—MB）升高、心电图改变及影像学检查显示肺炎。结论甲型H1N1流感的临床表现与一般季节性流感相似，但传染性较强。随着重症病例的增多，筛查时应加强心肌酶谱检测以及心电图和胸部X线检查，以便尽早发现甲型H1N1流感重症病例，降低病死率。Objective To screen influenza A （H1 N1 ） from patients in fever clinic. Methods Influenza A （ H1 N1 ） screening was performed from patients in fever clinic of Guangzhou No. 8 People＇ s Hospital during May 2 to October 31, 2009. Epidemiological data, clinical symptoms and the laboratory findings were analyzed. Results In 3 063 patients who received screening, 272 （8.88%） were diagnosed as influenza A （ H1 N1 ）, 23 （ 8.46% ） of whom were severe cases. Fever as the initial symptom was observed in 190 patients, and other frequent symptoms included cough, angina and headache, etc. Increased creatine kinase isoenzyme （CK-MB） , electrocardiogram change or pneumonia images appeared in severe cases. Conclusions Clinical symptoms of influenza A （ H1 N1 ） are similar to those of seasonal influenza but with higher infectivity. Myocardial enzyme tests, electrocardiogram and chest X ray examination should be taken for early diagnosis of severe cases.

关 键 词：流感 人 流感病毒A型 H1N1亚型 发热门诊 筛查 

分 类 号：R51[医药卫生—内科学]