新型鼻塞持续气道正压治疗新生儿低氧血症疗效分析  

Evaluating the curative effect of a new type nasal obstruction continuous positive airway pressure in neonatal hypoxemia

作　　者：王胜会[1] 雷小平[1] 郭琳[1] 董文斌[1] 李清平[1] 

机构地区：[1]泸州医学院附属医院新生儿科,四川泸州646000

出　　处：《中国优生与遗传杂志》2010年第2期84-85,128,共3页Chinese Journal of Birth Health & Heredity

摘　　要：目的回顾性的研究新型鼻塞持续气道正压(nCPAP)治疗新生儿严重低氧血症的疗效及安全性。方法以常规给氧无效的83例严重低氧血症患儿为研究对象,其中足月儿32例,早产儿51例。呼吸暂停33例,肺炎并呼吸衰竭(呼衰)21例,肺透明膜病19例,胎粪吸入综合征6例,新生儿湿肺4例。给予使用新型nCPAP治疗,观察治疗效果、并发症发生情况。结果给予nCPAP治疗后绝大多数患儿缺氧状态得到改善。治愈67例,16例效果不好转为气管插管行其他模式机械通气治疗。腹胀8例,心功能不全5例,鼻前庭皮肤部压迫伤2例,无一例发生气漏、慢性肺疾病和早产儿视网膜病。结论新型nCPAP治疗新生儿严重低氧血症操作方便,疗效满意,可以很好的控制温度和吸入氧的浓度,避免了因吸入纯氧、高浓度氧引起的视网膜病、慢性肺疾病等氧中毒性损伤。减少了气管插管的机会,降低了呼吸机相关性肺炎的发生率,相对比较安全。Objective：To retrospective investigate the curative effect and safety of a new type nasal obstruction continuous positive airway pressure in serious neonatal hypoxemia.Methods：83 newborns to trouble a serious hypoxemia after treating in common oxygen therapy,including 32 term infants and 51 preterm infants. 33 infants have apnea,21 infants have pneumonia symphyso-respiratory failure,19 infants have hyaline membrane disease,6 infants have meconium aspiration syndrome and 4 infants have wet lung of newborn. They are treated by a new type nasal obstruction continuous positive airway pressure,to overview the information of curative effect and concurrent disease.Results：The hypoxia condition of majority infants have been improved after giving nCPAP. There are 67 cases healing well and 16 cases are used tracheal intubation to introduction the mechanical ventilation. There are 8 neonats receive abdominal distension,5 newborns occur cardia insufficiency and 1 infant have compression trauma on nasal.None developments frequent hemorrhoid,chronic Pulmonary disease and preterm infant retinopathy.Conclusion：The curative effect of a new type nasal obstruction continuous positive airway pressure in neonatal hypoxemia is significant,it is convenient to operate. It can control the temperature and density of oxygen inspired contently,and avoid the injury of oxygen intoxication including retinopathy and chronic Pulmonary disease induced by breathing in straight oxygen and high density oxygen. It can reduce the possibility to tracheal intubation and cut down the incidence of breathing vent related pneumonia. It is safe.

关 键 词：鼻塞持续气道正压 低氧血症 新生儿 疗效 并发症 

分 类 号：R722.1[医药卫生—儿科]