L_(1～4)椎间盘ADC值、腰动脉血供与椎间盘退变程度的相关性分析  

Correlation of ADC values in lumbar intervertebral discs(1-4) and lumbar artery status with intervertebral disc degeneration

作　　者：李跃华[1,2] 孙万驹[3] 赵振国[1] 隋海晶[1] 杨昀[3] 

机构地区：[1]上海市浦东新区人民医院放射科,上海201200 [2]上海市交通大学医学院附属第六人民医院放射科,上海200233 [3]上海市浦东新区人民医院骨科,上海201200

出　　处：《第二军医大学学报》2010年第2期169-172,共4页Academic Journal of Second Military Medical University

基　　金：上海市浦东科技发展创新基金(PKJ2007-y08)~~

摘　　要：目的分析可疑腰椎病变患者L1-4椎间盘ADC值、腰动脉血供与相应平面椎间盘退变程度的相关性,评价ADC值对椎间盘退变的可能诊断价值,并探讨椎间盘退变的血供因素。方法可疑腰椎病变患者65例,年龄16-76岁,平均（52.3±28.5）岁;其中下腰痛并坐骨神经痛11例,下腰痛无坐骨神经痛16例,坐骨神经痛无下腰痛33例,跛行5例;病程1-57周,平均（13.4±6.3）周。对所有患者采用椎间盘弥散成像测定L1-4椎间盘ADC值,采用腰动脉MRA进行腰动脉成像,分析椎间盘ADC值、腰动脉血供与相应平面椎间盘退变程度的相关性。结果L1-4平面ADC值与各自平面椎间盘退变分级明显相关（P〈0.05）,退变程度越大,椎间盘ADC值越小。L1、L2、L3平面腰动脉血供分级与各自平面（L1-2、L2-3、L3-4）椎间盘退变程度分级明显相关（rs=0.823,P=0.016 3;rs=0.791,P=0.019 2;rs=0.835,P=0.010 3）;L4平面腰动脉血供分级与L4-5椎间盘退变程度分级无明显相关（rs=0.306,P=0.209 2）。结论MR弥散成像测得的腰椎间盘ADC值能反映L1-4腰椎退变程度;血供因素是部分节段椎间盘（L1-2、L2-3、L3-4）退变的重要影响因素。Objective To analyze the correlation of intervetebral disc degeneration with the diffusion values of lumbar vertebral discs and lumbar blood supply in patients with suspected lumbar intervertebral problems,so as to assess ADC value in diagnosis of intervertebral degeneration and the related blood supply.Methods Sixty-five patients with suspected lumbar intervertebral problems were included in the present study;they had a mean age of （52.3±28.5） years and an age range of 16-76 years.Eleven of them had low back pain complicated with sciatica,16 had low back pain without sciatica,33 had sciatica without low back pain,and 5 had intermittent claudication.The disease course was 1-57 weeks,with a mean of（13.4±6.3） weeks.MR angiography and diffusion imaging were performed to evaluate the status of lumbar arteries and to obtain the ADC values of L1-4,so as to analyze the correlation of ADC values,lumbar blood supply,and intervetebral disc degeneration.Results The ADC values of L1-4 were negatively correlated with the degeneration of lumbar discs（P〈0.05）.There was a relation between the artery status of L1,L2,and L3 with the degeneration of corresponding lumbar discs of L1-2,L2-3,and L3-4（rs=0.823,P=0.016 3;rs=0.791,P=0.019 2;rs=0.835,P=0.010 3）.The artery status of L4 and the L4-5 discs was not significantly correlated with degeneration of corresponding lumbar discs（rs=0.306,P=0.209 2）.Conclusion The ADC values of lumbar intervertebral disc can reflect the degeneration of L1-4,and degeneration of L1-2,L2-3,and L3-4 is correlated with the artery status of corresponding discs.

关 键 词：磁共振血管成像 弥散加权成像 腰动脉 椎间盘 

分 类 号：R681.533.1[医药卫生—骨科学]