14种食物不耐受血清特异性IgG抗体检测在临床中的应用价值  

Evaluation of clinical application of serum specific IgG antibody on 14 foods intolerance

作　　者：陈杰[1] 王轶[2] 张剑波[1] 汪智英[1] 董巍[1] 

机构地区：[1]四川省医学科学院.四川省人民医院临床医学中心实验室,四川成都610072 [2]四川省医学科学院四川省人民医院器官移植研究所,四川成都610072

出　　处：《实用医院临床杂志》2010年第1期67-69,共3页Practical Journal of Clinical Medicine

摘　　要：目的分析血清中14种食物不耐受特异性IgG抗体检测在临床中的应用价值,为临床相关疾病的诊治提供依据。方法对596例样本采用酶联免疫吸附法(ELISA)半定量检测血清中14种食物特异性IgG水平。结果患者组食物不耐受阳性率和14种食物血清特异性IgG抗体浓度均高于健康对照组,差异有显著性意义(P<0.05);4组症状组平均阳性率以蛋清/蛋黄最高(50.2%),其次为蟹(36.7%)、虾(31.4%)、牛奶(23.0%);平均IgG浓度也以蛋清/蛋黄最高(205.4U/ml),其次为牛奶(196.9U/ml)、西红柿(121.3U/ml)、猪肉(116.8U/ml)。结论患者体内产生食物特异性IgG抗体,提示患者症状与食物不耐受有关。及时明确不耐受食物,对临床相关疾病的诊治和预防具有一定的价值。Objective To analyze and evaluate the correlation of serum specific IgG antibody on 14 foods intolerance with patient symptom,and to provide a related marker for clinical diagnosis. Method Measure serum IgG level （semi-quantitative） in 596 samples by Enzyme-linked Immunosorbent Assay （ELISA）. Results The positive percentage of patients with higher serum specific IgG concentration in 14 foods intolerance is higher than control group（P 0.05）. Among the 14 foods intolerance,the positive percentage of egg white/yolk was the highest （50.2%）,followed by crab （36.7%）,shrimp （31.4%）,and milk （23.0%）. Egg white/yolk had the highest concentration of IgG antibody （205.4 U/ml）,too,followed by milk （196.9 U/ml）,tomato （121.3 U/ml）,and pork （116.8 U/ml）. Conclusion It is shown that specific IgG antibody is found in patient serum,which means there is correlation between food intolerance and patient symptom. Measure serum specific IgG antibody concentration in time and eliminate the allergic food from diet has certain importance in clinical diagnosis ,treatment and prevention of related diseases.

关 键 词：食物不耐受 特异性IGG抗体 

分 类 号：R446.6[医药卫生—诊断学]