甲硝唑的非破坏分析  

NONDESTRUCTIVE ANALYSIS OF METRONIDAZOLE POWDER

作　　者：任玉林[1,2,3] 李伟[1,2,3] 任玉秋[1,2,3] 张璐[1,2,3] 孙莹[1,2,3] 惠春[1,2,3] 

机构地区：[1]吉林大学化学系 [2]白城卫生学校 [3]长春医学高等专科学校药学系

出　　处：《中国医药工业杂志》1998年第11期509-511,共3页Chinese Journal of Pharmaceuticals

摘　　要：偏最小二乘（ＰＬＳ）法同近红外漫反射光谱法结合，非破坏分析了粉末药品甲硝唑。讨论了波长对ＰＬＳ定量预测能力的影响。校正样品和预测样品预测结果的相对标准误差分别为０．０８６６％和０．１５５７％。Metronidazole powder was analysed nondestructively by near infrared diffuse reflectance spectra combined with partial least squares (PLS) method. The influence of the wavelenghs on the capacity of quantitative prediction of PLS method was discussed. The relative standard errors of prediction for the calibration samples and prediction samples were 0.0866% and 0.1557% respectively. The results are satisfactory.

关 键 词：甲硝唑 药物分析 非破坏分析 偏最小二乘 

分 类 号：R978.6[医药卫生—药品] R914.1[医药卫生—药学]