重度卵巢过度刺激综合征的危险因素及妊娠结局分析  

Clinical Analysis of Risk Factor and Pregnancy Outcome of Ovarian Hyperstimulation Syndrome on Severe Cases

作　　者：殷文静[1] 范保维[1] 毛玲芝[1] 蔡倩芳[1] 廖碧翎[1] 邓群娣[1] 

机构地区：[1]广东省妇幼保健院妇产科,510010

出　　处：《岭南急诊医学杂志》2010年第1期29-30,17,共3页Lingnan Journal of Emergency Medicine

摘　　要：目的:探讨重度卵巢过度刺激综合征(OHSS)的危险因素及其对妊娠结局的影响。方法:回顾分析2005年1月～2009年7月在本院住院治疗的46例重度OHSS患者(OHSS组)和68例未发生OHSS的体外受精-胚胎移植(IVF-ET)患者(非OHSS组)的临床资料,比较两组患者的临床特征。结果:OHSS组与非OHSS组比较,两组患者的平均年龄、体重指数、PCOS发生率、卵泡数目和取卵数目差异均有显著性(P<0.05),而两组的不孕年限和身高因素差异无显著性。OHSS组患者的多胎妊娠率较非OHSS组患者高(P<0.05),而流产、异位妊娠、早产、分娩率差异无显著性。患者的平均年龄、注射HCG当日卵泡数目、PCOS和多胎妊娠率与重度OHSS发生率呈正相关(P<0.05)。结论:明确重度OHSS的危险因素及其对妊娠的影响,对于OHSS的防治具有重要的指导意义。Objective： To investigate the risk factor and pregnancy outcome of ovarian hyperstimulation syndrome （OHSS） on severe cases. Methods：46 cases of severe OHSS inpatients and 68 cases of non-OHSS patients whom received in vitro fertilization and embryo transfer （IVF-ET） treatment were retrospectively analyzed from Jan,2005 to Jul,2009.The patients were divided into OHSS group and non-OHSS group. The clinical characteristics were compared between them. Results：The mean age and body mass index were significantly lower while the PCOS rate,multiple pregnancy rate, amount of ovarian follicle and ova obtained were significantly higher in OHSS group than those in non- OHSS group （P〈0.05）. Among the infertility time, body height, abortion rate, ectopic pregnancy rate, premature delivery rate and delivery rate, there was no significant difference between the two groups（P〉0.05）. Conclusions：More attention should be paid to the risk factor and the influence to pregnancy outcome of severe OHSS during IVF-ET treatment to protect the patient＇s life.

关 键 词：卵巢过度刺激综合征 危险因素 妊娠结局 

分 类 号：R714.8[医药卫生—妇产科学]