对二氯苯毒性研究  

Study on Toxicity of P Dichlorobenzene

作　　者：尹先仁[1] 秦钰慧[1] 郭润荣[1] 张丽霞[1] 

机构地区：[1]中国预防医学科学院环境卫生监测所

出　　处：《卫生研究》1998年第6期377-378,共2页Journal of Hygiene Research

基　　金：卫生部科研基金

摘　　要：结果表明蓄积毒性作用不明显（蓄积系数＞５），对眼无刺激性，对皮肤无致敏作用，但在皮肤多次刺激试验中具有轻度刺激作用；亚急性吸入试验未见肝肾功能的损害及其病理组织学改变；遗传毒性研究表明，在Ａｍｅｓ试验和中国仓鼠肺细胞染色体畸变检测系统中，无致突变作用。对二氯苯属低毒性物质。The authors studied the toxicity of P Dichlorobenzene(P DCB). The results showed that the toxicity of P DCB was low.It has no accumulation(K>5), no eye irritation and no skin sensitization effects.But light skin irritation effect was observed.In sub acute inhalate exposure,damage on the function of liver and kindney was not observed.Genotoxic tests showed that tests in s.typhimurium strains TA 98 and TA 100 did not show any mutagenic potential.In Chinese hamster lung fibroblast CHL cell test system,it did not cause chromosomal aberrations.

关 键 词：对二氯苯 毒性研究 

分 类 号：R996[医药卫生—毒理学]