胎儿主动脉峡部与脐动脉血流阻力指标比值在预测胎儿生长受限中的意义  

Significance of the Ratio of Resistance Index of Blood Flow Between Fetal Aortic Isthmus and Umbilical Artery for Predicting Fetal Growth Restriction

作　　者：周燕[1] 夏飞[1] 顾欣贤[1] 高成珍[1] 

机构地区：[1]苏州大学附属第一医院妇产科,江苏苏州215006

出　　处：《医学临床研究》2010年第2期215-217,共3页Journal of Clinical Research

基　　金：江苏省苏州市科技计划项目（SS08037）

摘　　要：【目的】探讨胎儿主动脉峡部（AO）和脐动脉（UA）血流阻力指标比值在预测胎儿生长受限（FGR）中的意义。【方法】运用彩色多普勒超声检测30例28-40孕周的正常胎儿和30例FGR的AO和UA搏动指数（PI）、阻力指数（RI）、收缩期峰值流速与舒张末期流速比值（S／D），选用ROC曲线进行诊断临界点选择。【结果】FGR组胎儿AO各阻力指标均明显低于正常组胎儿（P〈0．01）；UA各组指标均高于正常妊娠组（其中S／D、PI值P〈0．01，RI值P〈0．05）；FGR组胎儿AO和UA各阻力指标比值明显低于于正常组胎儿（其中S／D、PI比值P〈0．01，RI比值P〈0．01）。以（SAO／DAO）／（SUA／DUA）〈0．63提示胎儿生长受限的敏感性和特异性分别为90．0％和70．0%。【结论】AO和UA血流阻力指标比值在预测胎儿生长受限有一定的准确性，并可以提高预测的敏感性。[Objective]To explore the significance of ratio of resistance index（RI） of blood flow between fetal aortic isthmus（AO） and umbilical artery（UA） for predicting fetal growth restriction（FGR）. [Methods] Color ultrasonography was used to detect the velocity, PI, S/D and RI values of AO and UA to get the ratios of AO to UA. The RI of fetuses in 30 normal pregnancy women and in 30 pregnancy women with FGR was calculated. ROC curve was used to get the critical point of diagnosis. [Results] Compared with the normal pregnancy group, FGR group had obviously lower levels of IR of AO（ P 〈0.01, P 〈0. 001, respectively） and higher levels of IR of UA P〈0.05, P 〈0.01, respectively）. The （SAO/DAO）/（SUA/DUA） 〈0.63 showed that the sensitivity and specificity of FGR were 90.0% and 70.0%, respectively. [Conclusion] The RI ratio of AO to UA can be used to predict the incidence of FGR, and increase the sensibility of prediction.

关 键 词：胎儿发育 胎儿疾病/诊断 主动脉 脐动脉 

分 类 号：R714.43[医药卫生—妇产科学]