老年非瓣膜病房颤并脑梗死42例临床分析  

Clinical Analysis of 42 Cases of Senile Nonvalvular Atrial Fibrillation Complicated with Cere- bral Infarction

作　　者：刘伟英[1] 唐烨晖[1] 张建国[1] 邬文敏[1] 袁荣[1] 

机构地区：[1]湖南怀化市第一人民医院,湖南怀化418000

出　　处：《医学临床研究》2010年第2期286-288,共3页Journal of Clinical Research

摘　　要：【目的】总结老年非瓣膜病房颤（NVAF）并脑梗死的临床特征。【方法】对354例住院急性脑梗死患者（NVAF组42例和非房颤组312例）进行回顾性分析，比较两组意识障碍、大面积脑梗死、脑梗死后出血、中线移位、反应性高血糖、并发上消化道出血发生率、重型神经功能受损情况及1个月内病死率。【结果】NVAF组意识障碍、大面积脑梗死、脑梗死后出血、中线移位、反应性高血糖及并发上消化道出血发生率高，神经功能受损严重，1个月内病死率均显著高于非房颤组（P〈0．05）。【结论】老年NVAF易致大面积脑梗死，并发症发生率高，是患者预后差的主要因素。进行预防性抗凝治疗是必要的措施。[Objective]To summarize the relation between senile nonvalvular atrial fibrillation （NVAF） complicated with cerebral infarction and ordinary cerebral infarction. [Methods] A total of 354 hospitalized patients with acute cerebral infarction （including 42 NVAF patients and 312 non NVAF patients） were retrospectively analyzed. The incidence of consciousness disorder, massive cerebral infarction, hemorrhage after cerebral infarction, midline shift, responsive hyperglycemia, hemorrhage in upper digestive tract, severe neu tonal damage and case fatality rate within one month were compared between two groups. [Results]As compared with non-NVAF patients, NVAF patients showed significantly higher incidence of consciousness disor der, massive cerebral infarction, hemorrhage after cerebral infarction, midline shift, responsive hypoglycemia, hemorrhage in upper digestive tract, severe neuronal damage and higher case fatality rates within one month （ P 〈0.05）. [Conclusion] Senile NVAF can easily result in massive cerebral infarction and may have higher incidence of complications. It has become a major cause of poor prognosis of those patients. Therefore, preventive anticoagulation treatment for NVAF patients is necessary.

关 键 词：心房颤动/并发症 脑梗塞/并发症 

分 类 号：R541.75[医药卫生—心血管疾病]