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作 者:谭飞[1] 赖维[2] 王海俊[1] 谢韶琼[1] 陆春[2] 樊国彪[1] 黄峥烨[1]
机构地区:[1]上海市皮肤病性病医院,上海200443 [2]中山大学附属第三医院皮肤科,广东广州510630
出 处:《临床皮肤科杂志》2010年第2期80-82,共3页Journal of Clinical Dermatology
摘 要:目的:探讨原发性和继发性干燥综合征(ss)的不同临床特点,指导临床的诊断和治疗。方法:回顾性分析67例干燥综合征患者的临床症状、实验室及辅助检查结果和治疗的异同。结果:67例患者中41例为原发性Ss,26例为继发性Ss。原发性Ss常以单一症状发病,猖獗龋发生率、角膜荧光染色阳性率、γ-球蛋白升高发生率均较高,肾脏损害以肾小管间质损害为主:继发性Ss大部分以复合症状起病,肾脏损害以肾小球损害为主,肺损害较原发性Ss更严重。结论:原发性与继发性Ss有不同的临床特点和实验室检查结果,临床上要注意两者的鉴别和治疗的选择。Objective: To study the different clinical characteristics of primary and secondary Sjogren's syndrome (Ss) patients. Methods: A retrospective study was performed on 67 patients with primary Ss (41 cases) and secondary Ss(26 cases). Results: There was a disparity between primary Ss and secondary Ss. The primary Ss often began with a single symptom, while secondary Ss with multiple symptoms, which is lack of specificity. Renal injury was one of the main symptoms in Ss. Tubular lesions were more often in primary Ss, while renal glomerulus impairment was more frequent in secondary Ss. Pulmonary lesions were worse in secondary Ss. The incidences of hyper-gammaglobulinemia was more often in primary Ss. Conclusions: The primary Ss was distinct from the secondary Ss in many respects. It is important to differentiate them and choose the right therapeutic regimens.
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