疟疾合并肾功能受损临床分析  

Clinical analysis of malaria patients complicated with damage to renal function

作　　者：邹洋[1] 冯曼玲[1] 王非[1] 栗绍刚[1] 齐志群[1] 李威[1] 吴赵永[1] 谷俊朝[1] 

机构地区：[1]首都医科大学附属北京友谊医院北京热带医学研究所,100050

出　　处：《中国热带医学》2010年第4期464-465,478,共3页China Tropical Medicine

摘　　要：目的探讨疟疾合并肾功能受损的临床特点及防治。方法对28例疟疾病例的临床资料进行回顾性分析。结果28例均输入性疟疾患者,其中恶性疟者14例,间日疟者10例,混合感染者4例。其中发展为急性肾功能衰竭,需血液透析治疗者,恶性疟2例和混合感染者1例。经抗疟,保护肾功能等治疗,治愈率100%。结论疟疾合并肾功能受损,抗疟治疗是根本措施,及时识别和合理治疗并发症是关键,加强对流动人口疟疾管理,预防为主要手段。Objective To describe the clinical features of malaria infection with damage to renal function. Methods Twenty-eight malaria eases were retrospectively analyzed. Results There were 14 faleiparum malaria cases and 10 vivax malaria cases and 4 mixed infections including 2 pf eases and a mixed infection complicated with damage to renal function. Acute renal failure （ARF） was seen mostly in Plasmodium faleiparum infections,but vivax malaria infection would occasionally result in renal impairment. The management includes appropriate treatment with antimalarials（Artemether, etc.）, supplement of fluid and electrolyte,and renal replacement therapy at the earliest stage. Conclusion Currendy,high quality intensive care, early institution of renal replacement therapy, and avoidance of nephrotoxic drugs are standard practice for management of ARF.

关 键 词：疟疾 急性肾功能衰竭 蒿甲醚 

分 类 号：R531.3[医药卫生—内科学]