甘草中甘草酸的提取及测定方法简述  

Determination and extraction of glycyrrhizic acid in licorice

作　　者：王珊[1] 黄怡[1] 曹蕾[1] 王成[1] 

机构地区：[1]咸阳师范学院化学系,陕西咸阳712000

出　　处：《化工科技》2010年第1期76-80,共5页Science & Technology in Chemical Industry

基　　金：陕西省教育厅专项科研计划资助项目(08JK482);咸阳师范学院专项基金项目(08XSYK109)

摘　　要：综述了甘草中有效成分甘草酸的提取、纯化和测定方法的研究概况。稀醇溶液对甘草酸的提取效果较好,添加稀氨水后可提高甘草酸的提取收率;超声波强化或微波辅助提取可提高甘草酸的提取效率并节约提取溶剂和提取时间,CO2超临界流体法无毒、高效且不需加热即可将甘草酸与溶质分离;薄层色谱(TLC)、高效液相色谱(HPLC)、毛细管电泳(CE)方法可实现甘草酸及甘草次酸含量的快速、准确测定。Extraction,purification and determination methods of glycyrrhizic acid in Licorice were surveyed in this paper. The extracting efficiency of dilute ethanol solvent for glycyrrhizic acid was higher than water extraction, and ammonia appended to ethanol solution can increase the effect of extraction. Ultrasound method, microwave-assisted method and supercritical CO2 fluid extraction were more effective than the conventional techniques, due to the short extraction time, low consumption of solution and energy. The modern analytical methods such as TLC. HPLC and CE can determine the content of glycyrrhizic acid rapidly and exactly.

关 键 词：甘草 甘草酸 提取 测定 

分 类 号：R284.2[医药卫生—中药学]