复配植物源杀菌剂的开发研究  

Exploratory Study of a Phytogenic Multi-formula Bactericide

作　　者：王帆[1,2,3] 杨静东[4,2,3] 王春梅[1] 石志琦[1] 

机构地区：[1]江苏省农业科学院食品质量安全与检测研究所,江苏南京210014 [2]江苏省食品质量安全重点实验室(省部共建国家重点实验室培育基地),江苏南京210014 [3]农业部食用农产品安全监控重点开放实验室,江苏南京210014 [4]江苏省东海县农业局,江苏东海222300

出　　处：《江西农业学报》2010年第2期87-89,共3页Acta Agriculturae Jiangxi

基　　金：江苏省农业科技自主创新资金(CX(09)103)

摘　　要：研究了植物源化合物肉桂醛、丁香酚、麝香草酚和单宁酸对5种常见致病菌（金黄色葡萄球菌、大肠杆菌、铜绿假单胞菌、肠炎沙门氏茵和单核细胞增生李斯特氏菌）的抑制作用。采用肉汤稀释法测定各成分对5种致病菌的最小抑茵浓度（MIC），在浓度范围19．53～2500μg／mL内，各成分对各致病菌均表现出了抑制活性。对化合物之间的相互作用也进行了研究，肉桂醛、丁香酚、麝香草酚和单宁酸两两复配后各成分的最小抑菌浓度都有所降低，采用部分抑菌浓度（FIC）判定表明它们之间存在协同增效的作用。The inhibitory effects of einnamaldehyde, eugenol, thymol and tannin against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella enteritidis and Listeria monoeflogenes were investigated in this study. The minimum inhibitory concentrations （MICs） of these compounds were determined by broth dilution method. All the compounds showed antibacterial activity when their concentrations ranged from 19.53 μg/mL to 2500 μg/mL. The interactions of these compounds were also investigated by calculating the fractional inhibitory concentrations （FICs） of every binate combination. The results indicated that there were synergism and additive effects among the compounds, which probabilizes cinnamaldehyde, eugenol, thymol and tannin to be developed to a phytogenic multi -formula bactericide.

关 键 词：植物源杀菌剂 致病菌 复配 协同作用 

分 类 号：S482.292[农业科学—农药学]