Histone code in the cross-talk during DNA damage signaling  

Histone code in the cross-talk during DNA damage signaling

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作  者:Thomas Vaissiere Zdenko Herceg 

机构地区:[1]Epigenetics Group, International Agency for Research on Cancer (IARC), 150 cours Albert Thomas, 69008 Lyon, France

出  处:《Cell Research》2010年第2期113-115,共3页细胞研究(英文版)

摘  要:Cells and organisms are targets of endogenous and exogenous genotoxic agents. Those hits induce different lesions of the DNA including single and double strand breaks, which in turn trigger the appropriate response. Deficiencies in DNA damage response lead to deregulation of critical cellular processes such as proliferation, cell cycle arrest, and apoptosis,

关 键 词:DNA损伤 组蛋白 信号 串扰 编码 细胞周期阻滞 细胞增殖 基因毒性 

分 类 号:Q523[生物学—生物化学] Q343.2

 

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