滇重楼地上部分与地下部分总皂苷止血、镇痛、抗炎作用比较  

Comparison of Hemostatic, Analgesic and Anti-inflammatory Effects of Total Saponins between the Aerial and Underground Parts of Paris polyphylla var. yunnanensis

作　　者：卜伟[1,3] 赵君[1] 沈志强[2] 程永现[1] 

机构地区：[1]中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室,昆明650204 [2]昆明医学院云南省天然药物药理重点实验室,昆明650031 [3]大理学院药学院,大理671000

出　　处：《天然产物研究与开发》2009年第B10期370-372,共3页Natural Product Research and Development

基　　金：云南省中青年学术技术带头人后备人才基金（No.2007PY01-48）

摘　　要：以宫血宁胶囊为阳性对照，观察滇重楼茎叶、果实与根茎总皂苷对小鼠尾尖出血时间的影响、对醋酸致小鼠疼痛扭体反应的影响以及对二甲苯致小鼠耳廓肿胀的影响，结果表明滇重楼根茎总皂苷的止血和抗炎作用均强于茎叶和果实的总皂苷作用；根茎、茎叶、果实的总皂苷镇痛作用相当。因此滇重楼茎叶、果实与根茎总皂苷均具有止血、抗炎和镇痛作用。The total saponin in the stems and leaves, fruits, and roots of Paris polyphylla var. yunnanensis was tested for their effects on mouse tail-tip bleeding time, acetic acid induced abdominal constriction in mouse and dimethylbenzene induced mouse ear edema. The results showed that hemostatie and anti-inflammatory effects of the roots saponin are more potent than those of the aerial parts. There is no distinct difference of the analgesic effect between the aerial parts and the roots saponin. We concluded that the total saponin from the foregoing parts of P. polyphylla var. yunnanensis all possess hemostatic, analgesic and anti-inflammatory effects.

关 键 词：滇重楼 地上部分 根茎 止血 镇痛 抗炎 

分 类 号：Q946.91[生物学—植物学] R285[医药卫生—中药学]