红景天软胶囊质量标准研究  

Study on the Quality Standard for Rhodiola Capsule

作　　者：娄灯吉[1,2] 芦启琴[1,2] 杨晓艳[1,2] 王环[1,2] 沈建伟[1,2] 张晓峰[1] 

机构地区：[1]中国科学院西北高原生物研究所,西宁810008 [2]中国科学院研究生院,北京100049

出　　处：《天然产物研究与开发》2009年第B05期227-229,共3页Natural Product Research and Development

摘　　要：本实验采用TLC法鉴别方中红景天苷及其苷元酪醇，采用甲醇：0．1％磷酸水为流动相的HPLC梯度洗脱法测定红景天软胶囊中红景天苷的含量，建立了红景天软胶囊的质量标准。该方法准确可靠、专属性强，能简便有效的控制该制剂的质量，可以在同-TIE色谱条件下同时检出红景天苷、酪醇的特征斑点。红景天苷在1．6～5．8峭范围内与峰面积有良好的线性关系，r=0．9996（n=5），平均加样回收率为99．27％，RSD为0．7％。In order to establish the quality control standard for Rhodiola capsule, salidroside and tyrosol were identified by TLC. The content of salidroside was determined by HPLC. This method was simple, accurate and specific, and could control the quality of this preparation effectively. Salidroside and tyrosol could be identified by TLC at the same time. Salidroside had the linear range of 1.6-5.8 μg（ n =5） ,r =0.999 6 with an average recovery of 99.27% and RSD of 0.7%.

关 键 词：红景天软胶囊 TLC HPLC 梯度洗脱 红景天苷 酪醇 质量标准 

分 类 号：Q946.91[生物学—植物学] R284.1[医药卫生—中药学]