妥洛特罗贴剂在婴幼儿喘息性疾病中的应用  

作　　者：熊琴 冼建妹 

机构地区：[1]珠海市妇幼医院,519000

出　　处：《当代医学》2010年第9期49-50,共2页Contemporary Medicine

摘　　要：目的观察妥洛特罗贴剂联合布地奈德雾化吸入治疗轻中度婴幼儿喘息性疾病的临床有效性和安全性。方法将122例轻中度婴幼儿喘息性疾病患儿随机分为治疗组和对照组。治疗组62例,对照组60例,两组均给予布地奈德溶液2ml雾化吸入及止咳化痰对症处理,合并感染者使用抗生素。对照组同时加入硫酸特布他林溶液1ml雾化,每日3次;治疗组采用妥洛特罗贴剂0.5mg,睡前一贴。比较两组咳嗽,喘鸣消失时间,平均住院日及不良反应发生率。结果治疗组和对照组疗效相当,无显著性差异,但妥洛特罗贴剂组不良反应小于硫酸特布他林雾化组。结论妥洛特罗贴剂联合布地奈德雾化吸入治疗轻中度婴幼儿喘息性疾病安全可靠,疗效显著。Objective Observe the clinical efficacy and safety of tulobuterol patches combined with budesonide inhalation in the treatment of mild to moderate asthmatoid diseases in infants and young children. Methods Randomly divide 122 cases of mild to moderate asthmatoid diseases in infants and young children into treatment group and the control group. 62 cases in treatment group, 60 cases in control group, insand both groups were given 2ml budesonide solution inhalation, cure cough, facilitate expectoration and use antibiotics on infected patients. At the same time the control group add lml terbutaline sulphate aerosol solution inhalation 3 times a day; while the treatment group use tulobuterol patches 0.5mg by bedtime. Compare the disappeared time of cough and wheezing, the average length of stay in hospital and the incidence of adverse reactions between two groups. Results The treatment group and control group have no significant differences in treatment effect, but the tulobuterol patches group has fewer adverse reactions than terbutaline sulphate aerosol group. Conclusion Tulobuterol patches combined with budesonide inhalation in the treatment of mild to moderate asthmatoid disease in infants and young children is safe and reliable, and have a significant effect.

关 键 词：婴幼儿喘息 妥洛特罗贴剂 布地奈德 雾化吸入 

分 类 号：R725.6[医药卫生—儿科]