实时动态血糖监测与胰岛素泵联合应用对2型糖尿病患者血糖控制的效果  

The efficacy of glucose controll by the combination of the Guardian ^(?)RT continuous glucose monitoring system and CSII in type 2 diabetes patients

作　　者：徐岩[1] 李春霖[1] 李剑[1] 田慧[1] 成晓玲[1] 

机构地区：[1]解放军总医院老年内分泌科,北京100853

出　　处：《中国糖尿病杂志》2010年第2期121-123,共3页Chinese Journal of Diabetes

摘　　要：目的评价实时动态血糖监测系统(Guardian RT CGMS)与持续皮下胰岛素输注(CSII)联合应用对T2DM患者血糖控制的影响。方法 18例T2DM患者佩戴Guardian RT CGMS连续3d,并于监测的第2天给予CSII治疗,根据实时血糖情况调整胰岛素用量。结果各时段血糖、平均血糖及血糖波动幅度均较治疗前显著下降(P均<0.01);高血糖、低血糖报警次数及持续时间均较治疗前显著减少。结论 Guardian RT CGMS能及时显示血糖变化值,反映血糖变化趋势,以此指导CSII中胰岛素的应用,可平稳有效控制血糖,预防血糖大幅度波动和低血糖的发生。Objective To evaluate an influence of the combination of the Guardian RT CGMS and continuous subcutaneous insulin infusion（CSII） in controlling blood glucose in type 2 diabetic patients. Methods A total of 18 type 2 diabetic subjects underwent a glucose monitoring with Guardian RT CGMS for 72 hours and treatment with CSII the next day. According to real time glucose levels and blood glucose profiles, we made treatments and adjusted the dose of insulin. We also observed the glycemic excursions when using Guardian RT CGMS and CSII. Results The mean blood glucose, mean amplitude of glyeemic excursions and mean blood glucose for every hour were reduced significantly after therapy versus pre-therapy（P〈0. 01）. The hyperglycemia and hypoglycemia warning times each day and the persistence times were significantly decreased. Conclusions Guardian RT CGMS can reflect blood glucose profiles, instruct the clinical use of insulin in CSH,avoid blood glucose big changing, especially hypoglycemia.

关 键 词：糖尿病 实时动态血糖监测系统 持续皮下胰岛素输注 

分 类 号：R587.1[医药卫生—内分泌]