镁基合金应用于生物医用材料的研究进展  

Research Developments of Magnesium Alloys as Biomedical Material

作　　者：葛淑萍[1] 王贵学[1] 沈阳[1] 张勤[1] 贾东煜[1] 

机构地区：[1]重庆大学生物工程学院生物流变科学与技术教育部重点实验室,重庆400044

出　　处：《材料导报》2010年第5期124-127,共4页Materials Reports

基　　金：科技部国际科技合作重点项目(2004DFA06400)

摘　　要：镁基合金具有较高的强韧性和加工性能以及较好的生物相容性,可应用于骨组织工程、整形外科以及血管支架中。而镁基合金在人体体液环境下的腐蚀性又反过来影响其使用寿命。采用适宜的改性方法不仅可以提高镁基合金的耐腐蚀性能,降低其生物降解速率,而且可以进一步提高其力学性能和表面生物活性。综述了镁基合金的力学相容性、生物相容性、可降解性以及针对以上性能的各种改性方法,并评述了国内外对镁基合金医用生物材料的应用研究概况。Magnesium alloys have been widely applied in bone tissue engineering, orthopedics and vascular stents due to their high toughness, processing performance and good biocompatibility. The corrosion of magnesium alloys in human body fluids limits their durability. It not only can improve their corrosion resistance and reduce their biological degradation rate, but also enhance their mechanical properties and surface biological activities with appropriate modification methods. As one kind of biomaterial, the biomechanical compatibility, biocompatibility, degradability and modification methods of magnesium alloys are reviewed, and their biomedical applications are summarized in this paper.

关 键 词：镁基合金 力学相容性 生物相容性 可降解性 

分 类 号：TS102.512[轻工技术与工程—纺织工程] TG146.22[轻工技术与工程—纺织科学与工程]