络石藤化学成分的研究  

Chemical constituents from Trachelosperomum jasminoides

作　　者：袁珊琴[1] 于能江 赵毅民[1] 徐斌[1] 姚志伟[1] 

机构地区：[1]军事医学科学院毒物药物研究所,北京100850

出　　处：《中草药》2010年第2期179-181,共3页Chinese Traditional and Herbal Drugs

基　　金：国家重大新药创制重大专项(2009ZX0931-002)

摘　　要：目的研究络石藤Trachelosperomum jasminoides的化学成分。方法采用色谱技术进行分离纯化,根据波谱学数据鉴定结构。结果从络石藤中分离得到4个单体化合物,分别鉴定为4-二甲基庚二酸(1)、东莨菪素(2)、去甲络石苷元-8-O-β-D-葡萄糖苷(3)及芹菜素-7-O-新橙皮糖苷(4)。结论化合物1为新化合物,化合物2为首次从该植物中分得。Objective To study the chemical constituents of Trachelosperomum jasminoides. Methods Chromatographic methods were used for the isolation and purification. Structures were elucidated on the basis of spectroscopic data. Results Four compounds were isolated from T. jasminoides and identified as 4-dimethyl heptanedioie acid （1）, seopoletin （2）, nortrachelogenin-8-O-β-D-glucopyranoside （3）, and apigenin-7-O-neohesperidoside （4）. Conclusion Compound 1 is a new compound and compound 2 is found in this plant for the first time.

关 键 词：络石藤 4-二甲基庚二酸 东茛菪素 

分 类 号：R284.1[医药卫生—中药学] R284.2[医药卫生—中医学]