血浆同型半胱氨酸水平与妊娠相关性疾病关系的研究进展  

Research Advance about the Relationship between Plasma Homocysteine Levels and Pregnancy-related Diseases

作　　者：安慧芳[1] 尚禹[1] 李楠[1] 毕新春[1] 

机构地区：[1]天津市第三中心医院妇产科,天津300170

出　　处：《中国慢性病预防与控制》2010年第1期104-106,共3页Chinese Journal of Prevention and Control of Chronic Diseases

摘　　要：血浆高同型半胱氨酸血症可引起妊娠期相关性疾病,如妊娠高血压、胎盘血管疾病、先天性心脏病、增加血小板黏附性和致妊娠丢失,严重者危及母子生命。补充叶酸、维生素B6和维生素B12有望降低妊娠相关疾病的发生,对于降低孕产妇及围产儿发病率及死亡率有重大意义。The high maternal hyperhomocysteinemia can cause related disease during the pregnancy, even endanger the living life of mother and fetus. Aggravated diseases such as pregnancy hypertension and complications hypertersive disorder and pregnancy, placental vascuvar disease, congenital heart disease, platelet abnormalities and pregnancy loss and soon. With the progress of pregnancy, levels of serum folie acid, vitamin B6 and vitamin B12 gradually reduced till the late pregnancy, resulting in obstacles from plasma bomocysteine to methionine, and forming high hyperhomocysteinemia. Therefore, supplementary folic acid, vitamin B6 and vitamin B12 are expected to reduce the incidence of pregnancy-related diseases. It＇s significant to reduce maternal and perinatal morbidity and mortality.

关 键 词：同型半胱氨酸 妊娠高血压病 妊娠期血小板异常 胎盘血管疾病 先天性心脏病 妊娠丢失 

分 类 号：R714.25[医药卫生—妇产科学]