高血压伴颈动脉粥样硬化与动态血压参数及其它危险因素关系研究  

The Study of the Relationship Between the Essential Hypertensives with Carotid Artery Artherosclerosis and Ambulatory Blood Pressure Monitoring Parameters and other Risk Factors

作　　者：董建新[1] 鲁跃华[2] 

机构地区：[1]嘉应学院医学院附属医院,广东梅州514031 [2]成都铁路中心医院心内科,四川成都610081

出　　处：《河北医学》2010年第2期166-169,共4页Hebei Medicine

摘　　要：目的:了解伴颈动脉粥样硬化的高血压病患者血压节律特点及血脂异常等其他心血管病危险因素水平是否有差异,探讨对颈动脉粥样硬化病变的影响因素。方法:对所有入选患者询问病史、体检并行动态血压监测(ABPM)、颈动脉超声及血生化检测。结果:颈动脉粥样硬化组(CAS组)男性患者比率、平均年龄、TC、LDL-C水平高于对照组,HDL-C水平低于对照组,24hSBP、dSBP、nSBP、24hPP、dPP、nPP水平及非杓型血压检出率高于无颈动脉粥样硬化组(对照组),差别有统计学意义(P值均<0.05)。结论:血压昼夜节律异常,非杓型血压、ABPM所示收缩压及脉压增大对CAS病变形成的影响更明显,男性比女性、年长、血脂异常程度愈重,对CAS病变形成有更明显的促进作用。Objective： To study the factor that have more effect to the carotid artery artherosclerosis by researching if there have significant differences in the level of blood pressure, the rhythm of blood pressure,the hyperlipemia and the level of other cardiovascular risk factors. Method： All selected patients were inquired case historys and physical examination, they were carried out ambulatory blood pressure monitoring, carotid ultrasound examination, blood biochemistry detection. Result： The ratio of male patients,mean age, the level of total cholesterol and low density lipoprotein cholesterol in carotid artery artherosclerosis group were higher than that in control group;and the level of high density lipoprotein cholesterol in carotid artery artherosclerosis group was lower than that in cgntrol group, there were statistical significance （ P 〈 0.05 ）. Conclusoin： There have more effect to the carotid artery artherosclerosis in the abnormality of circadian rhythm of blood pressure, Non - dipper blood pressure, systolic blood pressure and pulse pressure which were obtained by ambulatory blood pressure monitoring. It have more promotion to the carotid artery artherosclerosis in the patients of male, eldership, severity hyperlipemia.

关 键 词：高血压病 24H动态血压监测 颈动脉内膜中层厚度 颈动脉粥样硬化 

分 类 号：R544.1[医药卫生—心血管疾病]