苦碟子注射液治疗痰热腑实型急性期脑梗死临床研究  

Observation on therapeutic effect of Kudiezi injection in treating syndrome of phlegm-heat and bowel-repletion in patients with acute cerebral Infarction

作　　者：温静[1] 张连城[1] 张玉莲[1] 张允岭[2] 

机构地区：[1]天津中医药大学第二附属医院,300150 [2]北京中医药大学东方医院,100078

出　　处：《天津中医药大学学报》2010年第1期13-16,共4页Journal of Tianjin University of Traditional Chinese Medicine

基　　金：国家科技部973专项基金资助(2006CB504805)基于临床的内毒损伤络脉创新病因学研究

摘　　要：[目的]观察苦碟子注射液治疗痰热腑实型急性期脑梗死的临床疗效。[方法]将80例脑梗死患者随机分为2组,对照组采用西医常规治疗,治疗组在此治疗基础上加用苦碟子注射液。疗效评价指标采用神经功能缺损程度评分和中医临床证候计分法。[结果]治疗组总有效率为80%,对照组为52.5%,差异有统计学意义(P<0.01);卒中量表(NIHSS)评分治疗组明显优于对照组(P<0.05);治疗组在改善中医证候方面具有明显的统计学意义,疗效优于对照组。[结论]苦碟子注射液体在痰热腑实型脑梗死临床疗效上具有一定的意义,治疗组在改善中医证候方面优于对照组。[Objective] To observe the clinical curative effect of Kudiezi injection on cerebral infarction with syndrome of Phlegm-heat and Bowel-repletion. [Methods] Eighty patients with cerebral infarction were randomly divided into two groups. Patients in control group were treated with Western medicine and the treatment group with Kudiezi injection and Western medicine together. The function of neural system and traditional Chinese medicine symptoms were evaluated respectively in two groups and gave scores. [Results] The effective rate was 80 % in the treatment group and 52.5 % in the control group. There was very significant difference between the two groups （P〈0.01）, and the score of the National Institute of Health＇s Stroke Scale （NIHSS） and the evaluation of TCM symptom in the treatment group were better than those in the control group （P〈0.05）. [Conclusion] The Kudiezi injection has a definite therapeutic effect in treating patients with acute cerebral infarction in Phlegm-heat and Bowel-repletion. Compared with the control group, the treatment group shows obvious improvement on the evaluative scores of TCM symptoms.

关 键 词：脑梗死 苦碟子 痰热腑实型 

分 类 号：R255.2[医药卫生—中医内科学]