左炔诺孕酮皮下埋植避孕对育龄妇女骨矿物质密度的影响  

Effect of Levonorgestrel-Releasing Implants on Bone Mineral Density in Women of Reproductive Age

作　　者：盖凌 王晓青[2] 盖萍 姜慧 刘永红[5] 

机构地区：[1]山东省计划生育科学技术研究所优生遗传重点实验室,济南250002 [2]山东省滕州市计划生育服务站 [3]山东省省立医院 [4]山东省日照市东港区三庄计划生育委员会 [5]山东省医学影像研究所

出　　处：《中国计划生育学杂志》2010年第3期166-168,共3页Chinese Journal of Family Planning

摘　　要：目的:探讨应用左炔诺孕酮皮下埋植剂避孕和非激素宫内节育器(IUD)避孕对育龄妇女骨矿物质密度(BMD)的影响。方法:对比观察126例应用左炔诺孕酮皮下埋植剂的妇女和93例采用非激素IUD避孕妇女腰椎和股骨颈BMD。结果:一般检测特征在两组间类似,左炔诺孕酮皮下埋植剂平均使用期为35.2±6.7个月,与对照组相比,两组BMD差异无统计学意义。结论:左炔诺孕酮皮下埋植避孕对育龄妇女骨矿物质密度无不利影响。Objective： To compare the bone mineral density（BMD） between users of levonorgestrel-releasing implants and nonhormonal-IUD users.Methods： A total of 126 current users of levonorgestrel-releasing implants and 93 nonhormonal-IUD users were enrolled in the study.The BMDs of the lumbar spine and femoral neck were measured by dual energy X-ray absorptiometry.Results： The demographic characteristics were similar in both groups.The mean duration of levonorgestrel-releasing implants was 35.2±6.7 months.The mean BMDs of lumbar spine and femoral neck between the users of levonorgestrel-releasing implants and the nonhormonal-IUD users were no significant differences.Conclusion： Levonorgestrel-releasing implants have no adverse effects upon BMD in women of reproductive age.

关 键 词：左炔诺孕酮 皮下埋植剂 骨矿物质密度 避孕 

分 类 号：R169.4[医药卫生—公共卫生与预防医学]