烟酒茶嗜好因素与中国女性乳癌关系的Meta分析  

Meta-ANALYSIS OF POSSIBLE RELATIONSHIP BETWEEN HOBBIES OF SMOKING,ALCOHOL AND TEA WITH BREAST CANCER IN CHINESE WOMEN

作　　者：王萍玉[1] 谢书阳[2] 张帅[2] 

机构地区：[1]滨州医学院卫生学教研室,山东烟台264003 [2]滨州医学院生物化学与分子生物学研究室,山东烟台264003

出　　处：《齐鲁医学杂志》2010年第1期3-7,共5页Medical Journal of Qilu

基　　金：山东省高等学校科技计划项目(J09LF11)

摘　　要：目的综合分析评价烟酒茶嗜好因素与中国女性乳癌的关系，探索乳癌的危险因素。方法收集我国1994-2008年间有关烟酒茶嗜好因素和乳癌的病例对照研究文献，利用Meta分析的方法对检索出的符合要求的文献进行再分析，定量综合评价烟酒茶嗜好与乳癌的关系。结果纳入本次Meta分析的文献共8篇，乳癌病例共1580例，对照者共2399例。吸烟合并OR＝1．89（95％CI：1．27～2．81），饮酒合并OR=0．73（95％CI：0．53～0．99），饮茶合并OR=0．84（95％CI：0．70～1．02）。结论吸烟尤其是被动吸烟是乳癌发生的危险因素，倡导全民戒烟，减少乳癌的发生；饮酒饮茶与乳癌关系有待进一步研究。Objective To analyze the association of hobbies of smoking, alcohol and tea with breast cancer and its risk factors in Chinese women. Methods Data of case-control studies on breast cancer in China from 1994 to 2008 were collected and analyzed synthetically by using Meta-analysis. Results Eight literatures met the criteria were enrolled in the Meta-analysis, in which, 1 580 cases were breast cancer and 2 399 controls. For smoking, summary odds ratio （OR） was 1.89, 95% confidence interval （1.27-2.81）; for alcohol, OR：0.73,95% CI（0.53-0.99）; and for tea, OR：0.84,95% CI（0. 70-1. 02）. Conclusion Smoking, passive smoking in particular, significantly increases the risk of breast cancer, while alcohol and tea are to be investigated.

关 键 词：乳腺肿瘤 病例对照研究 危险因素 META分析 

分 类 号：R181.2[医药卫生—流行病学] R737.9[医药卫生—公共卫生与预防医学]