老年原发性高血压患者血压昼夜节律与左室重构的相关性研究  

The relationship between left ventricle remolding,ventricular pemature beats and heart rate variability in patients with essential hypertension

作　　者：张强[1] 乔鹏[2] 杨丽红[1] 

机构地区：[1]郑州大学第二附属医院心内科,郑州450014 [2]郑州大学基础医学院生理教研室,郑州450000

出　　处：《中国实用神经疾病杂志》2010年第5期3-6,共4页Chinese Journal of Practical Nervous Diseases

摘　　要：目的探讨老年原发性高血压(EH)患者血压昼夜节律与左心室肥厚的关系。方法对158例EH患者伴或不伴左心室肥厚(LVH)和129例正常健康老年人(对照组)采用水银血压计和24h动态血压(ABPM)各指标进行组间及组内比较,同时与心脏超声资料进行相关性分析。结果(1)EH患者伴LVH组和NLVH组与对照组24h各时间段的血压均值有统计学意义(P<0.05);LVH组中24hSBP、dSBP、nSBP均明显高于NLVH组(P<0.05),而24hDBP、dDBP、nDBP的差异无统计学意义(P>0.05)。(2)LVH组白昼收缩压、舒张压水平与夜间差异无统计学意义(P>0.05),而NLVH组白昼收缩压、舒张压水平高于夜间(P<0.05)。(3)LVH非勺型组发生率高于勺型者(P<0.05)。(4)收缩压水平与LVMI的相关性比舒张压密切,而夜间收缩压、舒张压水平与LVMI的相关性比白天更密切。结论老年EH患者存在明显节律紊乱,且左室肥厚主要与收缩压和脉压水平有关。Objective To analyze the relationship between left ventricle hypertrophy（LVH）, ventricular pemature beats （VPBS）and heart rate variahility（HRV）in patients with essential hypertension（EH）. Methods Total 158 EH patients complicated with LVH and NLVH and 129 normal controls received examinations by 24 hours Holter monitoring electrocardiogram. Results Both of the incidence and grades of ventricular pemature beats for 24 hours in LVH group were obviously higher than that in control group. The parameters of HRV were not significantly different between two groups（P〉0. 05）. Conclusion The incidence of severe ventricular arrhythmia in EH patients with LVH rises obviously,but no correlativity exists between LVH and HRV.

关 键 词：老年 原发性高血压 左心室重构 动态血压 

分 类 号：R544.1[医药卫生—心血管疾病]