急性脑梗死脑损害的病理机制和中西医疗效观察  

Pathological mechanism of brain damage and observation on the effect of integrated traditional with western medicine in the treatment of acute cerebral infarction

作　　者：任金生 

机构地区：[1]河南商丘市第二人民医院,商丘476002

出　　处：《中国实用神经疾病杂志》2010年第5期14-16,共3页Chinese Journal of Practical Nervous Diseases

摘　　要：目的阐述急性脑梗死(acute cerebral infarction,ACI)脑损害的病理机制和观察化痰活血通络汤对ACI的疗效。方法174例病人分为治疗组(88例)和对照组(86例)。对照组行常规治疗和银杏叶提取物6ml加入生理盐水或5%葡萄糖注射液250ml稀释后静滴,qd;治疗组在对照组的基础上加用化痰活血通络汤口服,1剂/d,分2次服。2组均治疗2周为1疗程,4周后判定疗效。结果治疗组总有效率92.05%,对照组总有效率76.75%,经统计分析差异有统计学意义(P<0.05)。结论银杏叶提取物合用化痰活血通络汤治疗ACI具有显著的疗效。Objective To investigate the pathological mechanism,and observe the effect of huatan houxue tongluo decoction in the treatment of acute cerebral infarction. Methods One hundred and seventy-four patients were divided into two groups randomly, treatment group（n=88） and control group（n= 86）. The 86 patients of the control group （male 49 cases, female 37cases,average age 58. 4） only received routine drugs and Ginkgo biloba extract （EGb）6 m] in 5% glucose injection 250 ml,iv gtt,qd. The 88 patients of treatment group （make 47cases,female 41cases,average age 58.6） received the treatment of control group and huatan huoxue tongluo decoction,bid, po,conventional therapy for 14 days. After treatment of four weeks clinical efficacy were observed. Results The total effective rate of the treatment group was 92.05%0, while the control group was 76.75%. A significant difference existed by Ridit analysis （P〈0.05）. Conclusion EGb with huatan huoxue tongluo decoction is effective in the treatment of acute cerebral infarction.

关 键 词：急性脑梗死 脑损害 病理机制 银杏叶提取物 化痰活血通络汤 

分 类 号：R743.33[医药卫生—神经病学与精神病学]