初诊2型糖尿病患者微血管病变与相关危险因素分析  

Newly Diagnosed Type 2 Diabetic Patients with Microvascular Disease and Related Risk Factor Analysis

作　　者：王生龙[1] 

机构地区：[1]河南省安阳市第二人民医院,455000

出　　处：《慢性病学杂志》2010年第3期196-198,共3页Chronic Pathematology Journal

摘　　要：目的:分析初诊2型糖尿病患者微血管病变(周围神经病变、视网膜病变、糖尿病肾病)与其相关危险因素关系。方法:对120例新诊断的2型糖尿病患者进行神经传导速度、眼底荧光造影和尿微量白蛋白及相关指标测定,计算微血管病变的患病率,并对相关因素分析。结果:(1)初诊患者中糖尿病周围神经病变的患病率为34.6%,糖尿病视网膜病变的患病率为15.4%,糖尿病肾病的患病率为13.4%。(2)年龄、空腹血糖、餐后2h血糖、收缩压、舒张压、糖化血红蛋白、总胆固醇均为糖尿病周围神经病变的独立危险因素。(3)糖化血红蛋白、尿微量白蛋白、收缩压为糖尿病视网膜病变独立危险因素。结论:初诊2型糖尿病患者有一定微血管病变患病率,应强化对血压、血糖、血脂相关危险因素的干预以控制和延缓糖尿病微血管病变的发生、发展。Objective：To summarize the analysis of newly diagnosed type 2 diabetic patients with microvascular disease （peripheral neuropathy, retinopathy, diabetic nephropathy） associated with the relationship between risk factors. Methods： 120 cases of newly diagnosed type 2 diabetes patients with nerve conduction velocity, fundus fluorescein angiography, urinary albumin and related parameters were measured to calculate the prevalence of microvas- cular disease, and then analyze related reasons. Results： （1） newly diagnosed patients with diabetic peripheral neu- ropathy prevalence rate was 34.6 %, the prevalence of diabetic retinopathy was 15.4%, the prevalence of diabetic nephropathy was 13.4%. 12） age, fasting glucose, 2 hours postprandial blood glucose, systolic blood pressure, diastolic blood pressure, and glyeosylated hemoglobin, total cholesterol of diabetic peripheral neuropathy are independent risk factors. （3） glycosylated hemoglobin, urinary albumin, systolic blood pressure as independent risk factors for diabetic retinopathy. Conclusions： Newly diagnosed type 2 diabetic patients with microvascular disease have a certain prevalence rate should strengthen the blood pressure, blood sugar, blood lipid-related risk factors for intervention to control and delay the occurrence and development of diabetic mieroangiopathy.

关 键 词：糖尿病 2型/并发症 糖尿病血管病变/流行病学 因素分析 统计学 人类 

分 类 号：R587.1[医药卫生—内分泌]