无溶剂条件下活性炭固载硫酸催化酮和芳香醛的Cross-Aldol缩合反应  

Activated Carbon Supported Sulfuric Acid as an Efficient Catalyst for Cross-Aldol Condensation of Ketones with Aromatic Aldehydes under Solvent-Free Conditions

作　　者：马峰[1] 李立强[1] 郝海娥[1] 苏艳[1] 刘万毅[1] 

机构地区：[1]宁夏大学化学化工学院宁夏大学能源化工重点实验室,银川750021

出　　处：《有机化学》2010年第3期419-423,共5页Chinese Journal of Organic Chemistry

基　　金：国家973前期预研(No.2006CB708606)资助项目

摘　　要：以活性炭固载硫酸(acsa)为催化剂,在无溶剂条件下催化酮和芳香醛的Cross-Aldol反应,成功合成了16个相应的α,β不饱和缩合产物,反应时间30～100min,产率可达65%～94%.该方法不仅反应时间短,产率高,催化剂可以重复利用,后处理简单,而且还对环境友好.产物经熔点,IR,1HNMR,13CNMR确证.Aromatic aldehydes underwent cross-aldol condensation with ketones in the presence of acti- vated carbon supported sulfuric acid （acsa） under solvent-free conditions to afford 16 corresponding α,β-unsaturated aldol products in reaction time of 30- 100 rain, and the good yields from 65% to 94%. This method provides a simple, fast and clean reaction, using a small quantity of catalyst and a simple workup procedure. The catalyst could be reused. The structures of the products were characterized by IR, 1H NMR and 13C NMR techniques.

关 键 词：无溶剂 Cross—Aldol缩合 活性炭固载硫酸 酮 芳香醛 

分 类 号：O643.32[理学—物理化学]