我国甲肝免疫水平现状分析——基于多水平Meta分析结果  

ANALYSIS OF CURRENT STATUS OF HEPATITIS A’S IMMUNIZATION LEVELS IN CHINA-BASED ON MULTILEVEL META-ANALYSIS

作　　者：秦莎莎[1] 廖贵蓉[1] 裴小琴[1] 王晓雯[1] 李晓松[1] 朱彩蓉[1] 

机构地区：[1]四川大学华西公共卫生学院卫生统计学教研室,成都610041

出　　处：《现代预防医学》2010年第6期1020-1022,共3页Modern Preventive Medicine

摘　　要：[目的]了解我国甲型肝炎免疫水平现状,为建立合理的甲肝免疫策略提供参考。[方法]搜集中文科技期刊数据库（维普期刊数据库1996-2008）和中国期刊全文数据库（CNKI1996-2008）中有关中国各地区甲肝免疫现状相关研究资料,采用多水平Meta分析对研究结果进行综合。[结果]共26篇文献符合纳入标准,0-25岁甲肝抗体阳性率随年龄增长变化呈递增趋势,年龄每增加1岁,抗体阳性率上升1.3%;25岁以上人群甲肝抗体阳性率变化趋于平缓,平均甲肝抗体水平是76.7%。[结论]5岁以下儿童是甲肝免疫的重点人群,根据目前中国甲肝免疫现状建立适合中国国情的免疫策略是今后研究的方向。[Objective] To present current immunization levels of hepatitis A in China, so as to provide basis for establishing reasonable immunization strategy. [Methods] The VIP database and CNKI database from 1996 to 2008 were searched for the literatures about immunization levels of hepatitis A in China. Multilevel Meta analysis was used to summarize the immunization levels of hepatitis A in China. [Results] 26 pieces of papers were included according to the specific criteria. The anti- bodies levels of hepatitis A increase by 1.3% per year among people from age 0 to 25 in Chinese. The immunization levels reach to a plateau at 25 years old, the average immunization level showed stable, and the average positive rate of anti-hepatitis A antibodies was 76.7% over 25 years old. [Conclusion] Children under 5 years old are the high risk people of hepatitis A immunization people. According to the current status, establishing China’s cost-effective strategy on Hepatitis A immunization is the direction of future study.

关 键 词：甲肝抗体阳性率 多水平Meta分析 免疫现状 

分 类 号：R512.61[医药卫生—内科学]