心力衰竭患者甲状腺激素水平与心功能的关系  

Relationship between thyroid hormone and cardiac function in patient with congestive heart failure

作　　者：高伟[1] 袁春花[1] 何美[1] 

机构地区：[1]解放军第二军医大学上海长征医院南京分院心脏病科,南京210015

出　　处：《江苏医药》2010年第4期411-412,共2页Jiangsu Medical Journal

摘　　要：目的探讨充血性心力衰竭(CHF)患者甲状腺激素水平与心功能的关系。方法用放射免疫法(RIA)分别测定72例CHF患者(CHF组)和53例(对照组)的血清促甲状腺素(TSH)、总三碘甲状腺原氨酸(TT3)、总四碘甲状腺原氨酸(TT4)、游离甲状腺原氨酸(FT3)、游离甲状腺素(FT4)水平,并作超声心动图测定左室射血分数(LVEF)。结果CHF组TT3、FT3水平明显低于对照组(P<0.05);CHF组TT3水平与LVEF呈显著正相关(P<0.01)。结论甲状腺激素水平的变化可作为判断CHF严重程度的参考指标,对治疗及预后有一定临床意义。Objective To study the relationship between thyroid hormones and cardiac function in the patients with congestive heart failure（CHF）.Methods The serum levels of TSH,TT3,FT3,TT4 and FT4 were examined in 72 patients with CHF（group CHF）and 53 normal people（group C）.The left ventricular ejection fraction（LVEF）was observed by echocardiography as well.Results The levels of TT3 and FT3 in group CHF were markedly lower than those in group C（P0.05）.The level of TT3 in group CHF was positively correlated to LVEF（P0.01）.Conclusion The alteration of serum thyroid hormones can be taken as a refered marker for evaluating the severity and predicting the prognosis of CHF.

关 键 词：充血性心力衰竭 甲状腺激素 

分 类 号：R541[医药卫生—心血管疾病]