具有亚纳米级精度的自校正离焦定位系统的设计  

Design of Self-adjustable Off-focus Positioning System with Subnano Precision

作　　者：王晓暄[1] 杨俊东[2] 胡志祥[1] 瞿安连[1] 

机构地区：[1]华中科技大学生物化学和生物物理研究所 [2]93253部队44分队

出　　处：《计算机与数字工程》2010年第3期127-129,共3页Computer & Digital Engineering

摘　　要：提高时间分辨率和空间分辨率,是单微粒跟踪技术的主要发展方向。基于离焦定位技术的自校正离焦定位系统有效地提高了单微粒跟踪过程中获取信息的实时性和精确性,使对蛋白质、囊泡等作全细胞范围的三维亚纳米级实时跟踪成为可能。The main development direction of single particle tracking technology is to improve its space and time resolution.We designed a self-adjustable off-focus positioning system based on off-focus image analysis,which efficiently increases the timeliness and accuracy of single particle tracking system and makes it possible to track single protein or vesicle in three dimensions,in whole cell,and in real time with subnanometer precision.

关 键 词：单微粒跟踪 自校正离焦定位 Z轴位移控制 

分 类 号：Q6[生物学—生物物理学]