PET与CT对淋巴瘤化疗疗效评价的比较  

Compare ^(18)F-FDG PET Imaging with CT Imaging in the Evaluation of Chemotherapy of Lymphoma

作　　者：王军凯[1,2] 冯惠茹[1] 郭喆[1] 陆相东[1] 于杨洁[1] 于芳[1] 

机构地区：[1]北京军区总医院核医学科,北京100700 [2]山西医科大学第二临床医学院,太原030001

出　　处：《医学综述》2010年第6期952-954,共3页Medical Recapitulate

摘　　要：目的探讨18氟-氟代脱氧葡萄糖(18F-FDG)正电子发射计算机断层显像(PET)与计算机断层显像(CT)对淋巴瘤化疗疗效评价的异同。方法32例淋巴瘤患者化疗前后分别行PET/CT检查,首先分析CT图像,对淋巴瘤化疗的疗效作出评价,然后分析PET图像,再次评价淋巴瘤化疗疗效,比较2次疗效评价的差别。每位患者随访12～21个月。结果PET与CT评价淋巴瘤化疗疗效的符合率分别为96.9%、75.0%,二者比较差异有统计学意义(P=0.026)。结论PET对淋巴瘤化疗疗效的评价优于CT,然而,PET的评价存在假阳性,仍需要结合临床作出判断。Objective To compare fluorine 18 fluorodeoxyglucose （^18F-FDG） positron emission tomography （PET） imaging with computed tomography （CT） imaging in the evaluation of chemotherapy of lymphoma. Methods 32 patients were Collected who engaged ISF-FDG PET/CT both before chemotherapy and after chemotherapy. Response was evaluated respectively with CT and PET. All patients were followed up for 12 - 21 months. Results The coincidence of PET and CT was 96.9% ,75.0% respectively. There was significant difference between PET and CT in the evaluation of chemotherapy of lymphoma（ P = 0. 026 ）. Conclusions The use of FDG PET may be superior assessment of response to chemotherapy than the use of CT, but it may cause false positive, the result should combine with the clinic.

关 键 词：淋巴瘤 化疗 计算机断层扫描 正电子发射计算机断层扫描 

分 类 号：R817.4[医药卫生—影像医学与核医学] R816.3[医药卫生—放射医学]