广东省1起学校甲型H1N1流感暴发疫情调查  

Investigation and control of influenza A(H1N1) outbreak at a school in Guangdong Province

作　　者：龙其穗[1,2] 孙立梅[1] 郭汝宁[1] 杨忠伟[3] 余大年[3] 刘文锦[3] 梁侨任 

机构地区：[1]广东省疾病预防控制中心,广东广州510300 [2]广东省现场流行病学培训项目 [3]台山市疾病预防控制中心

出　　处：《华南预防医学》2010年第1期25-28,32,共5页South China Journal of Preventive Medicine

摘　　要：目的通过对广东省1起学校甲型H1N1流感聚集性疫情调查与控制,分析疫情特点及控制措施实施效果,为社区甲型H1N1流感疫情控制提供参考依据。方法采用主动搜索、问卷调查等方法对2009年6月26日广东省台山市报告的1起学校甲型H1N1流感暴发疫情进行调查,并用描述性流行病学方法进行分析;采集病例咽拭子标本用Real-time RT-PCR方法进行甲型H1N1流感病毒核酸检测。结果该疫情涉及台山市某小学10个班级中的9个;经病例搜索共报告流感样病例61例,全部为学生,罹患率为11.9%(61/514),临床症状主要以发热、咳嗽、咽痛和头痛为主;指示病例发病时间为6月19日,发病高峰为6月24日,末例病例发病时间为6月30日,疫情持续12 d。同期实行居家观察密切接触者314人,家庭内二代病例仅出现2例。对其中12例流感样病例采集咽拭子标本,经检测甲型H1N1流感病毒核酸均呈阳性。结论该起疫情为1起学校甲型H1N1流感暴发疫情,感染来源可能与海外返乡华侨中输入性甲型H1N1流感病例或隐性感染者引起社区甲型H1N1流感感染有关。Objective Through investigation and control of an outbreak of influenza A（H1N1） at a school in Guangdong,to analyze the epidemic features and control measure effects,thus providing reference basis for community influenza A（H1N1） prevention and control.Methods To investigate the influenza A（H1N1） outbreak aggregated epidemic at a school reported in Taishan County of Guangdong Province with active searching and questionnaire survey,and analyze it with descriptive epidemiological method.Throat swabs of patients were collected for influenza A（H1N1） virus nuclear detection.Results The epidemic involved 9 classes out of 10 in the affected primary school,and 61 influenza-like illness（ILI） cases were found（all students,attack rate 11.9%,61/514） through active case searching.The index case presented on June 19th,while the last on June 30th,and the epidemic lasted for 12 days,with peak on June 24th.A total of 12 throat swabs of ILI cases were detected positive for influenza A（H1N1） virus nucleic acid.Conclusion The origin of the influenza A（H1N1） influenza outbreak was possibly caused by introduced cases or inapparent infections of home-returning overseas Chinese.

关 键 词：甲型H1N1流感 学生 疾病暴发流行 

分 类 号：R511.7[医药卫生—内科学]