生物医用聚乳酸纤维增强壳聚糖棒材  

Bioabsorbable Polylactic Acid Fiber Reinforced Chitosan Composite Rod for Biomedical Materials

作　　者：胡晓兰[1] 谢鹏辉[1] 林勤[1] 王雯皓[1] 申丙星[1] 董炎明[1] 

机构地区：[1]厦门大学材料学院,福建厦门361005

出　　处：《厦门大学学报（自然科学版）》2010年第2期293-296,共4页Journal of Xiamen University：Natural Science

基　　金：福建省自然科学基金(E0710025);厦门大学科技创新项目(XDKJCX20053010)

摘　　要：利用原位沉析法制备了聚乳酸纤维/壳聚糖复合棒材,对复合棒材的微观形貌、力学性能进行了表征.有机聚乳酸纤维和有机壳聚糖基体具有良好的相容性,纤维表面还会因氢键等作用和基体产生物理吸附及一定的分子链缠结,SEM结果表明,纤维与基体间形成了良好的界面作用.复合棒材因聚乳酸纤维的加入有效地提高了弯曲强度和模量.当添加8%(质量分数)11 mm长的纤维时,复合材料弯曲强度达到108.9 MPa,比壳聚糖提高了54.9%,复合棒材弯曲模量达到4.74 GPa,比壳聚糖提高了170.9%.聚乳酸纤维和壳聚糖均具有良好的生物相容性和可降解性,这种复合材料在可吸收内固定材料方面将具有广阔的用途.A polylaetic acid fiber reinforced chitosan composite was fabricated by in-situ precipitation for internal fixation of bone fracture. Scanning electron microscopy（SEM） was done to characterize surface morphology of the polylactic acid fiber/chitosan composites. It would be good compatibility between organic polylactic acid fibers and organic chitosan matrix. SEM images revealed that a good interfacial interaction was obtained in the composites by the in-situ precipitation processing. And a ductile fracture of polylactic acid fiber was observed via SEM image due to physical adsorption and macromolecule chain intertwist between the interfaces of the polylactic acid fiber and the chitosan matrix. Considering that fiber length and concentration are important factor in the fiber enhanced polymer matrix composites,polylactic acid fiber length and concentration were studied chiefly in the composites. The results of mechanical properties indicated that the polylactic acid fiber showed significant improvement in the polylactic acid fiber/chitosan com- posites. There was a optimum value in the effects on polylactic acid fiber concentration on flexural strength and flexural modulus. However,the flexural modulus of the composites were increased with increasing polylactic acid fiber length in no more than 14 tara. The flexural strength and flexural modulus of the composite with 8% （by mass） polylactic acid fiber in 11 mm length were 108. 9 MPa and 4.74 GPa,respeetively,which were 54.9% and 170.9% higher than neat chitosan rod. This kind of biodegradation and hipabsorbable chitosan matrix reinforced composite will be widely used in the field of internal fixation in surgery.

关 键 词：壳聚糖棒材 聚乳酸纤维 增强 骨钉 

分 类 号：O636[理学—高分子化学]