狭叶落地梅化学成分的研究  

Studies on the Chemical Constituents of Lysimachia paridiformis Franch. var. stenophylla Franch.

作　　者：张援虎[1] 张吉明[1,2] 唐丽佳[1] 黄筑艳[3] 何丽[1] 杨小生 

机构地区：[1]贵州省中国科学院天然产物化学重点实验室,贵州贵阳550002 [2]贵阳中医学院,贵州贵阳550001 [3]贵州大学化学与化工学院,贵州贵阳550003

出　　处：《时珍国医国药》2010年第3期584-585,共2页Lishizhen Medicine and Materia Medica Research

基　　金：国家"973"前期重大基础研究研究专项(No.2007CB516813);中国科学院"西部之光"计划资助项目;贵州省中药现代化项目[黔科合农字(2006)5032号];贵州省优秀人才省长资金项目[黔省专合字(2006)83号]

摘　　要：目的研究狭叶落地梅Lysimachia paridiformis Franch. var. stenophylla Franch.的化学成分。方法采用多种分离技术对狭叶落地梅乙醇提取物的氯仿层和水层部分进行分离和纯化,根据其理化常数和光谱数据进行结构鉴定。结果从狭叶落地梅的全草中分离得到6个化合物,经鉴定为β-谷甾醇（I）、胡萝卜苷（Ⅱ）、Alternariol（Ⅲ）、2,5-二羟基苯甲酸甲酯（Ⅳ）、Alternariol monomethyl ether（V）、华中冬青素（Ⅵ）。结论化合物Ⅰ-Ⅴ均为首次从该种植物中分离得到。Objective To study the chemical constituents of Lysimachia paridiformis Franch.var.stenophylla Franch.Methods Various chromatographic techniques were used to isolate the constituents from the chloroform and water fractions of Lysimachia paridiformis Franch.var.stenophylla Franch.,and their structures were identified by spectral and chemical methods.Results Six compounds were isolated and identified as β-sitosterol（I）,Daucosterol（Ⅱ）,,Alternariol（Ⅲ）,Methyl-2,4-dihydroxybenzoate（Ⅳ）,Alternariol monomethyl ether（V）,Huazhongilexin（Ⅵ）.Conclusion Compounds（Ⅰ）-（V） were obtained from this plant for the first time.

关 键 词：狭叶落地梅 化学成分 

分 类 号：R284.1[医药卫生—中药学]