雌激素、胎盘生乳素、钙、磷与妊高征的关系  

Research on the Relationship Between Estrogen Human Placental Lactogen, Calcium, Phosphorus and Pregnancy-in-duced Hypertension(PIH)

作　　者：张玉洁[1] 李国梁[2] 

机构地区：[1]广州市第一人民医院妇产科,510180 [2]中山医科大学第一附属医院妇产科,510080

出　　处：《广东医学》1998年第12期909-910,共2页Guangdong Medical Journal

摘　　要：目的：探讨雌激素、胎盘生乳素、钙在妊高征发病中的作用及其相互关系。方法：采用放射免疫法及离心分析钙试剂，测定了42例妊高征患者血清雌二醇、胎盘生乱素、钙、磷及尿钙、磷的含量，34例同期门诊正常孕妇作为对照组。结果：轻度妊高征患者血清雌二醇明显增加（P＜0．05）。重度妊高征患者血清胎盘生乳素显著减少（P＜0．05）。轻、中、重度妊高征患者血钙、尿钙含量显著降低（P＜0．01，P＜0．01，P＜0．01）。血磷、尿磷含量显著升高（P＜0．05，P＜0．01，P＜0．01）。结论：雌二醇升高、血嫣降低可能在妊高征的发生过程中起一定的作用。Objective:To study the role estrogen, human placental lactogen,calcium and phosphorus take part in the pathogenesis of pregnancy induced hypertension.Mthods:Fourty -twowomen with PIH and thiryt -four normal term-pregnant womet were enrolled for study.The serumal of estrogen,Human placental latogen ,calcium,phoshorus concentrationwere measured with sensive radiommassary and atomic sbsorption spectrophotometry.Results:The level of serumal estrogenin the mild PIH group is significantly higher than that of normal prenancy(P<0.05).Human placental lactogen is significantly low in severe PIH patients (P<0.05). The more severe in PIH patients,The lower level of serumal and urinary calcium as well as the higher level of serumal and urinary phosphorts.Conclusion:The increase of estrogen may be one of the important factors responsible for the pathophysiologic changs of PIH.

关 键 词：雌二醇 胎盘生乳素 钙 磷 妊娠高血压 

分 类 号：R714.246[医药卫生—妇产科学]