参附注射液治疗18例急性有机磷农药中毒性休克的疗效观察  

Therapeutic effect of Shenfu injection in treatment to 18 patients with acute organophosphorus intoxication combined with shock

作　　者：张建新[1] 梁东良[1] 李雪亮[1] 杨亚勤[1] 

机构地区：[1]新乡医学院第一附属医院,453100

出　　处：《中国医学创新》2010年第8期53-54,共2页Medical Innovation of China

摘　　要：目的探讨参附注射液治疗急性有机磷农药中毒性休克的临床疗效。方法18例急性有机磷农药中毒性休克的患者为治疗组，在常规抗休克、清除毒物、解毒药物治疗的基础上加用参附注射液，观察用药治疗后6h、12h和24h心率、血胩，判断疗效。对照组是末使用参附注射液治疗的16例急性有机磷农药中毒性休克患者。结果治疗组在用药治疗后6h和12h的心率、血压与对照组比较有明显差异，而24h差异不明显。治疗组的总有效率为88．89％，对照组的的总有效率仅为56．25％，两者比较有明娩差异。结论参附注射液在治疗急性有机磷农药中毒性休克方面有明显的疗效。Objective To assess the clinical therapeutic effect of Shenfu injection in treatment to the patients with acute organophosphorus intoxication （ AOPI ） combined with shock. Methods Eighteen patients with AOPI combined with shock were divided into treatment group, and they were treated by these ways,including anti - shock and eliminated organo-phosphorus and using anti -poisoning medicine and Shenfu injection,and then their blood pressure, heart rate of 6 hours, 12 hours and 24 hours after medicine treatment were observed and recored, and their clinical therapeutic effect were assessed in the last ; control group were sixteen patients with AOPI combined with shock who they were not gived Shenfu injection, their observation index was the same with the treatment group. Results Blood pressure, heart rate of 6 hours, 12 hours of the treatment group remained significant variance, but those changes were small in 24 hours. The therapeutic effective rate of treatment group was 88. 89% and the therapeutic effective rate of control group was 56. 25%, and they remained significant variance. Conclusion Shenfu injection has better effects in treatment to patients with AOPI combined with shock.

关 键 词：参附注射液 有机磷农药 中毒性休克 

分 类 号：R595.4[医药卫生—内科学]