热应激对训练大鼠白介素2(IL-2)和自由基代谢的影响  

The Effect of IL-2、Free Radicals in Rats after Heat Stress

作　　者：尹斯年[1] 仇乃民[1] 郭成吉[1] 

机构地区：[1]盐城工学院体育部,江苏盐城224003

出　　处：《北京体育大学学报》2009年第12期76-78,共3页Journal of Beijing Sport University

摘　　要：为了探讨热应激和运动对大鼠白介素2(IL-2)和自由基代谢的影响,对大鼠进行为期6周的运动训练,并在运动末次施加热应激,测定大鼠外周血液白介素2(IL-2)含量、SOD活性、MDA含量、SOD/MDA,并分析各项指标之间的相关性。结果:1)热应激组大鼠血清中IL-2含量、SOD活性和SOD/MDA都显著低于对照组,而MDA含量显著高于对照组。2)运动训练组与非运动训练组在热环境下相比,大鼠血清中IL-2的含量、SOD活性和SOD/MDA有升高趋势,但没有显著性变化,MDA含量低于对照组,变化有显著性。3)IL-2、SOD活性、MDA含量、SOD/MDA相关性研究发现:大鼠血清中的IL-2含量与SOD活性、SOD/MDA呈现正相关,与MDA呈现负相关。In order to explore the effects of exercise and heat stress on IL-2,free radicals and regulating correlation in SD rats,the experiment is designed to make rats in exercise training for 6 weeks and add heat stress in the last training.The IL-2、SOD、MDA and SOD/MDA in peripheral blood and their correlation were measured.The results：1） After 6 weeks exercise training,the IL-2、SOD、and SOD/MDA in heat stress group and exercise training plus heat stress group were significantly lower than those in control group,while the MDA in exercise training plus heat stress group was significantly higher than those in control group.2） Compared with the group without any training under heat stress,the rats in the training group have higher IL-2、SOD、SOD/MDA in their blood serum,but the correlation is insignificant.The MDA in exercise training group was lower significantly under heat stress.3） Related analysis finds that the serum IL-2 has negative correlation with MDA and positive correlation with SOD and SOD/MDA.

关 键 词：热应激 运动训练 IL-2 自由基 

分 类 号：R87[医药卫生—运动医学]