参七虫草胶囊对慢性阻塞性肺疾病患者氧化／抗氧化失衡的临床研究  

Clinical research of Shenqichongcao capsule on oxidant/antioxidant imbalance in patients with chronic obstructive pulmonary disease

作　　者：郑为超[1] 张念志[2] 

机构地区：[1]安徽理工大学医学院郑为超,安徽省淮南232001 [2]安徽中医学院第一附属医院张念志

出　　处：《中国基层医药》2009年第12期2119-2120,共2页Chinese Journal of Primary Medicine and Pharmacy

基　　金：国家自然科学基金资助项目（30472216）

摘　　要：目的观察中药参七虫草胶囊对慢性阻塞性肺病（COPD）患者氧化／抗氧化失衡的影响。方法选择治疗组和对照组各30例的COPD患者，观察两组患者用药前后的证候积分变化以及其SOD、LPO、NO等指标的变化；并与健康组对照。结果COPD患者的SOD、LPO均较正常人降低，经参七虫草胶囊治疗前后差异有显著性（P〈0．01）；而对照组则无显著性差异。结论参七虫草胶囊对COPD患者的自由基损伤有一定的改善作用。Objective To observe the effect of Shenqichongcao capsule on oxidant/antioxidant imbalance in patients with chronic obstructive pulmonary disease （COPD）. Methods Selected 30 COPD patients from treatment group and control group respectively. Preand post treatment,the changes of points of Syndromes and their SOD, LPO and NO of patients were observed and compared with normal group. Results The level of SOD and LPO of COPD patients were lower than normal group with shenqichongcao capsule. There was significant difference before and after treatment （ P 〈 0.01 ）. The control group had no significant difference. Conclusion The effect of Shenqichongcao capsule on the free radical injury in patients with COPD had some improving effect.

关 键 词：参七虫草胶囊 肺疾病 慢性阻塞性 氧化 抗氧化 临床研究 

分 类 号：R259[医药卫生—中西医结合]