垂直捆绑胃成形术与胃旁路手术治疗肥胖的Meta分析  

Vertical-banded gastroplasty versus gastric bypass for obesity:a Meta-analysis of randomized controlled trials

作　　者：田宏亮[1,2] 田金徽[1] 袁浩[1,3] 葛赛[1,3] 唐震[1,2] 杨克虎[1] 

机构地区：[1]兰州大学循证医学中心,甘肃兰州730000 [2]兰州大学第二临床医学院,甘肃兰州730000 [3]兰州大学第一临床医学院,甘肃兰州730000

出　　处：《中国实用外科杂志》2010年第3期217-220,共4页Chinese Journal of Practical Surgery

基　　金：兰州大学循证医学中心"循证医学创新项目"(2009LDEBM-B);国家大学生创新性实验计划项目

摘　　要：目的系统评价垂直捆绑胃成形术与胃旁路手术治疗肥胖症的临床疗效及其临床应用价值。方法计算机检索全面收集垂直捆绑胃成形术与胃旁路手术治疗肥胖症的随机对照试验,检索时间截止至2009年4月。采用Cochrane系统评价手册文献质量评价标准评价纳入研究质量,用RevMan5.0软件进行Meta分析。结果共纳入4个随机对照试验,各试验间基线均可比。Meta分析结果显示:在1年后体重指数减小量及体重减轻比率上,胃旁路手术优于垂直捆绑胃成形术,而在手术时间和术后并发症方面,垂直捆绑胃成形术则优于胃旁路手术。结论在治疗肥胖的外科术式选择中,胃旁路手术在减重效果上优于垂直捆绑胃成形术,但其术后并发症也不容忽视。Objective To compare the surgical outcome and investigate the clinical value between vertical-banded gastroplasty and gastric bypass for obesity. Methods It searched related databases and identified randomized controlled trials of vertical-bamled gastroplasty versus gastric bypass for obesity. The quality of the included studies was evaluated by Handbook recommend standard. Data were analyzed by RevMan 5.0 from the Cochrane Collaboration. Results Four randomized controlled trials were included, and the baseline data of each trial were comparable. Meta-analysis showed that gastric bypass had better effectiveness than vertical-banded gastroplasty in body mass index （BMI） decrease and excess body weight loss one year later. However, vertical-banded gastroplasty had less operation time and complication than gastric bypass. Conclusion Gastric bypass treatment for obesity is better than vertical-banded gastroplasty in weight loss. But we should notice the complications after the gastric bypass.

关 键 词：垂直捆绑胃成形术 胃旁路手术 META分析 

分 类 号：R6[医药卫生—外科学]