合成α-芳基-β-硝基乙基膦酸酯的新方法  

A New Method to Synthesize a-Aryl-p-Nitroethylphosphonates

作　　者：李玉桂[1] 王国洪[1] 张殿坤[1] 刘廷仰[1] 缪方明[2] 刘小兰[2] 曹金鸿 郭杭州 

机构地区：[1]南开大学元素有机化学研究所 [2]天津师范大学化学系 [3]中国军事医学科学院

出　　处：《高等学校化学学报》1989年第4期373-378,共6页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金

摘　　要：本文研究了酸性亚磷酸酯与α-芳基-β-硝基烯烃在三甲基氯硅烷和缚酸剂存在下的Arbuzov-Michael反应。不需制备硅烷化的亚磷酸酯,即可得到产率高的Ia-n,其结构由元素分析、IR、1H NMR和MS证实。这类分子中磷原子上的O,O-二烷基为磁不等价基团的结论亦为X-射线晶体结构分析所证实。This paper reports a one-pot reaction of the Arbuzov-Michael addition of acidic phosphites to α-aryl-β-nitroalkenes. The reaction was carried out smoothly with an excess of trimethylchlorosilane and acid-binding agents, giving high yields of addition products I a-n . The structures of these compounds were characterized by elemental analysis, IR, 1H NMR and MS. It was found that in these molecules the O,O-dialkyl groups on the phosphorus atom were unequivalent. This fact was also confirmed by the X-ray structure determination of one representative compound, I j.

关 键 词：有机磷化合物 膦酸酯 合成 

分 类 号：O627.51[理学—有机化学]