儿童血培养病原菌分布与耐药性分析  

Distribution of Bacteria Detected from Blood Culture of Pediatric Patients and Analyses of Antibiotic Resistance

作　　者：汪俭[1] 刘红娟[2] 

机构地区：[1]安徽省立儿童医院心内科,安徽合肥230051 [2]安徽省立儿童医院检验科,安徽合肥230051

出　　处：《中华医院感染学杂志》2010年第5期741-742,共2页Chinese Journal of Nosocomiology

摘　　要：目的了解儿童血培养病原菌的分布及耐药性,为临床合理使用抗菌药物提供依据。方法采用全自动血培养仪进行血培养,用西门子AUTOSCAN4细菌鉴定及药敏分析仪进行鉴定和药敏试验。结果送检的2286份血培养标本共分离病原菌197株,其中革兰阳性菌140株占71.1%,革兰阴性菌57株占28.9%;革兰阳性菌对青霉素、氨苄西林耐药率高达>95.0%,对利萘唑胺、利福平敏感,未发现对万古霉素耐药的菌株。结论儿童血培养以革兰阳性菌为主,多药耐药菌常见,临床医师要重视药敏结果,严格用药指征,延缓病原菌耐药。OBJECTIVE To investigate the distribution of pathogenic bacteria in blood culture of pediatric patients and observe the antibiotic resistance of these bacteria in order to provide the reference for clinical antimicrobial agents usage. METHODS The blood samples of pediatric patients were cultured with blood culture apparatus. Siemens Autoscan 4 was used to identify the bacteria and conduct the drug resistance test. RESULTS From the 2286 blood samples received,we identified 197 strains of pathogens in which Gram-positive cocci accounted for 71.1% and Gram-negative bacilli for 28.9%.Niether strains of Gram-postive bacteria were found resistant to vancomycin. CONCLUSIONS Gram-postive bacteria are the main pathogens detected from the blood culture of pediatric patients. Multiresistant strains are common.We should recognize drug sensitive test results and the indication of antibiotics application to reduce the occurrence of bacterial resistance.

关 键 词：儿童 病原菌 血培养 耐药性 

分 类 号：R378[医药卫生—病原生物学]