北京市社区居民血脂及冠心病主要危险因素异常及边缘异常的流行特征  

Prevalence of dyslipidemia and borderline dyslipidemia and other risk factors of coronary heart disease in residents from Beijing communities

作　　者：王家宏[1] 胡大一[1] 傅媛媛[2] 孙艺红[1] 王桂莲[1] 管绯[1] 王劲松[2] 余金明[2] 

机构地区：[1]北京大学人民医院心脏中心,100044 [2]同济大学医学院公共卫生教研室

出　　处：《中华心血管病杂志》2010年第2期175-180,共6页Chinese Journal of Cardiology

基　　金：北京市科学技术委员会科技计划项目（D0906002040191）

摘　　要：目的调查北京市社区居民血脂及冠心病危险因素异常及边缘异常的流行病学特征，探讨北京市防治冠心病的方向。方法2007年6月至8月，分层整群随机抽样调查北京市社区居民10054名，采取问卷调查、体格检查和生化检测的方法，进行主要冠心病危险因素及血脂异常的调查。结果经年龄、性别标化后，北京社区居民高胆固醇血症、高低密度脂蛋白胆固醇血症、低高密度脂蛋白胆固醇血症和高甘油三酯血症的患病率分别是9．3％、2．56％、18．79％和16．84％，而处于胆固醇边缘升高的比例为23．96％。北京社区居民中血脂异常的患病率为31．23％，而处于血脂边缘异常的居民占23．30％。经年龄、性别标化后，71．17％的居民伴有冠心病主要危险因素，20．23％的居民伴有边缘异常的危险因素。高血压、糖尿病发病率分别为41．57％、11．08％，吸烟和肥胖的发生率分别是35．81％和22．89％。相对于理想状态，具有1项冠心病危险因素边缘异常人群患血脂异常的相对风险（OR）为1．668（95％CI：1．319～2．110）；具有2项冠心病危险因素边缘异常人群患血脂异常的OR为2．537，（95％CI：1．989～3．235）；具有≥3项冠心病危险因素边缘异常人群患血脂异常的OR为3．203，（95％CI：2．007—5．114）。结论北京社区居民血脂异常及冠心病主要危险因素的发生率较高，超过1／5的居民处于冠心病主要危险因素的边缘异常状态。具有边缘危险及冠心病主要危险的人群是今后北京市人群防治的重点。Objective To investigate the prevalence of dysllpidemia and borderline dyslipidemia and other coronary heart disease （CHD） risk factors in residents from Beijing communities. Methods Resident samples were selected by random cluster multistage method. Serum lipid level and CHD factors were obtained through questionnaire, physical examination and biochemical analysis during June 2007 to August 2007 from 10 054 residents. Results Age- and sex-adjusted standardized prevalence of hypercholesterolemia, high low-density lipoprotein cholesterolemia, low high-density lipoprotein cholesterolemia, and triglyceridemia were 9. 3% ,2. 56% , 18.79% and 16. 84% , respectively. Incidence of borderline hypercholesterolemia was 23.96%. Incidence of dyslipidemia and borderline dyslipidemia was 31.23% and 23.30% respectively, 71.17% residents have at least 1 CHD major risk factor and 20. 23% residents were in borderline CHD risks. Prevalence of hypertension, diabetes, smoking and obese was 41.57%, 11.08%, 35. 81% 和 22. 89%, respectively. The odds ratio for dyslipidemia （95% confidence interval）in residents having 1 borderline CHD risk factor（RF）, 2 RF, and 3 RF versus none RF was 1. 668, （95% CI： 1.319-2. 110） , 2. 537 （95% CI： 1. 989-3. 235 ） , and 3. 203 （95% CI：2. 007-5. 1 14 ）. Conclusions The prevalence of dyslipidemia of residents from Beijing communities is higher the average level of China （25.1%）. Over 1 out of 5 residents were in increased risk for borderline dyslipidemia or CHD risks. Intensive control of dyslipidemia and CHD risk factors are warranted in Beijing residents.

关 键 词：血脂异常 冠状动脉疾病 危险因素 流行病学 

分 类 号：R541.4[医药卫生—心血管疾病]