艾滋病合并HIV视网膜病变85例临床分析  

Clinical characteristics of non-infected retinopathy in patients with Acquired Immunodeficiency Syndrome

作　　者：杨娅玲[1] 石英[1] 何太雯[1] 卢洪洲[1] 

机构地区：[1]上海市复旦大学附属公共卫生临床中心,上海201508

出　　处：《中国艾滋病性病》2010年第1期1-3,9,共4页Chinese Journal of Aids & STD

基　　金："十一五"国家科技重大专项:艾滋病合并结核分枝杆菌感染人群治疗策略研究(2008ZX10001-008)~~

摘　　要：目的探讨艾滋病(AIDS)病人艾滋病病毒(HIV)视网膜病变的发病特点及临床表现特征。方法回顾273例有眼底照片的AIDS病人的资料,分析85例有HIV视网膜病变病人的CD4+T淋巴细胞计数、棉絮斑部位及数量、出血部位、眼别等,探讨HIV视网膜病变的发病特点和临床表现。结果273例AIDS病人中,发现有HIV视网膜病变的85例,发病率为31.14%。单、双眼均可发病,主要表现为眼底棉絮斑,大多部分伴有出血,单纯出血和Roth斑较少。大多位于眼底后极部,可自行消退;HIV视网膜病变病人的CD4+T淋巴细胞计数小于200细胞/μl,86%的病人CD4+T淋巴细胞计数低于100细胞/μl,近50%的病人CD4+T淋巴细胞计数低于50细胞/μl;不同CD4+T淋巴细胞水平间患眼棉絮斑数量比较,差异无统计学意义;各水平间棉絮斑、出血构成比比较差异无统计学意义。结论AIDS病人视网膜病变主要表现为棉絮斑,出现在细胞免疫水平较低的病人。随着免疫功能降低而发病率增加。AIDS病人应做常规眼科检查。Objective To explore the clinical characteristics of HIV retinopathy in Acquired Immunodeficiency Syndrome （AIDS） patients.Methods Eighty-five cases of AIDS patients with HIV retinopathy were recorded.The CD4^＋T lymphocyte count,wool cotton spots number,the site of wool cotton spots and haemorraghe patches,eyes were analyzed retrospectively.Results The incidence of HIV retinopathy in this series was 31.14 percent.It was characterized by wool cotton spots,hemorrhage patches and Roth patches.The CD4^＋ T lymphocyte count was lower than 100cells/ul mainly.There was no statistical difference in the comparision of the number of wool cotton spots among different CD4^＋ T lymphocyte count levels.Conclusions The ciinical characteristics of HIV retinopathy are wool cotton spots,hemorraghe and Roth patches.The lower the CD4^＋T lymphocyte count,the higher the incidence rate of HIV retinopathy.AIDS patients should be examined by ophythalmologist routinely.

关 键 词：艾滋病 艾滋病病毒视网膜病变 CD4^+ T淋巴细胞计数 

分 类 号：R512.91[医药卫生—内科学]